Global Statistics

All countries
547,145,332
Confirmed
Updated on June 23, 2022 9:27 pm
All countries
519,394,584
Recovered
Updated on June 23, 2022 9:27 pm
All countries
6,346,678
Deaths
Updated on June 23, 2022 9:27 pm

Global Statistics

All countries
547,145,332
Confirmed
Updated on June 23, 2022 9:27 pm
All countries
519,394,584
Recovered
Updated on June 23, 2022 9:27 pm
All countries
6,346,678
Deaths
Updated on June 23, 2022 9:27 pm
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Does Pfizer Vaccine Prevent Covid

Myth: Researchers Rushed The Development Of The Covid

Covid vaccine: what does the Pfizer vaccine news mean? – BBC News

FACT: Studies found that the two initial vaccines are both about 95% effective and reported no serious or life-threatening side effects. There are many reasons why the COVID-19 vaccines could be developed so quickly. Here are just a few:

  • The COVID-19 vaccines from Pfizer/BioNTech and Moderna were created with a method that has been in development for years, so the companies could start the vaccine development process early in the pandemic.
  • China isolated and shared genetic information about COVID-19 promptly, so scientists could start working on vaccines.
  • The vaccine developers didnt skip any testing steps, but conducted some of the steps on an overlapping schedule to gather data faster.
  • Vaccine projects had plenty of resources, as governments invested in research and/or paid for vaccines in advance.
  • Some types of COVID-19 vaccines were created using messenger RNA , which allows a faster approach than the traditional way that vaccines are made.
  • Social media helped companies find and engage study volunteers, and many were willing to help with COVID-19 vaccine research.
  • Because COVID-19 is so contagious and widespread, it did not take long to see if the vaccine worked for the study volunteers who were vaccinated.
  • Companies began making vaccines early in the process even before FDA authorization so some supplies were ready when authorization occurred.

Moderna: At Least 80%

Moderna’s vaccine was 69.5% effective at preventing COVID-19 with symptoms between the first and second dose, with a true value between 43.5% and 84.5%. There was a fairly wide range because the number of people that caught COVID-19 in the trial during this time period was low.

The 69.5% figure includes the 13 days before protection starts, so the real percentage could be higher.

There were a small number of people in Moderna’s trial about 7% that didn’t get their second dose for unknown reasons. In this group, the shot was 50.8% effective at preventing COVID-19 with symptoms for up to 14 days after the first dose and 92.1% effective after 14 days.

It is unclear how well one shot of the vaccine protects against hospitalization and death because not many people got severe COVID-19 two in the vaccine group and four in placebo.

Evans said that you get at least 80% protection and probably better than 90% for Moderna’s vaccine against COVID-19 with symptoms after a single dose for 28 days. After 28 days it was unclear because it hadn’t been tested. Again, this was based on his overall reading of the FDA data, he said.

When Does It Start Working

After receiving a COVID-19 vaccine, it takes weeks for your immunity to build. According to the CDC, full protection occurs two weeks after the second dose of the Pfizer-BioNTech or Moderna COVID-19 vaccines, or two weeks after the single-dose Johnson & Johnson vaccine.

Although it takes a second dose to reach full protection for the Pfizer-BioNTech and Moderna vaccines, data suggests that a significant immune response occurs about two weeks after the first dose. For example, an FDA briefing document for Moderna’s emergency use authorization application listed an overall efficacy of 50.8% between days one to 14 and an efficacy of 92.1% occurring after 14 days for one dose.

A CDC report that tracked almost 4,000 healthcare personnel, first responders, and other frontline workers under real-world conditions found that the mRNA vaccines were 80% effective at least 14 days following the first dose and 90% effective at least two weeks after the second dose.

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Q: What Safety Data Did The Fda Evaluate To Authorize The Pfizer

A: The available safety data to support the EUA include 37,586 of the participants enrolled in an ongoing randomized, placebo-controlled international study, the majority of whom are U.S. participants. These participants, 18,801 of whom received the vaccine and 18,785 of whom received saline placebo, were followed for a median of 2 months after receiving the 2nd dose. This is consistent with the recommendations set forth in the FDAs October 2020 Guidance on Emergency Use Authorization for Vaccines to Prevent COVID-19.

The most commonly reported side effects were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain, and fever. Side effects typically started within two days of vaccination and resolved 1-2 day later. Of note, more people experienced these side effects after the second dose than after the first dose, so it is important for vaccination providers and recipients to expect that that there may be some side effects after either dose, but even more so after the second dose.

The FDA also evaluated additional safety data from the larger database that included participants enrolled later during the study who had shorter follow-up . The FDA determined that the findings were similar to those in the population of participants with a median follow-up of 2 months after the 2nd dose.

Efficacy In Young People

What You Should Do If You Accidentally Lose Your COVID ...

Following Medsafe Provisional Approval, the decision to vaccinate young people aged 1215 years has been approved by Vaccine Ministers, Health Officials and Cabinet.

Pfizers study in 12- to 15-year-olds looked for signs of a strong immune response to the vaccine. Pfizer reported 100 percent efficacy in this age group .

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Florida Doctor: This Devastating Covid Surge Didnt Need To Happen

Experts caution against relying solely on one real-world study in determining effectiveness against infection. But other studies trying to establish the effectiveness of the vaccines at preventing infection have also generally shown declines against Delta, with some estimates in the same ballpark as the new CDC study.

The studys findings fit with the overall narrative of the Delta era of the pandemic.

In the spring, as it became clear that the vaccines were preventing the vast majority of infections, the CDC advised that vaccinated people no longer needed to wear masks. But as Delta took off, it became clear that Delta was causing breakthrough infections as well as symptomatic breakthrough infections at higher rates than other forms of the virus.

Scientists also concluded that vaccinated people who were still infected with Delta could transmit the virus to others . The findings led to the CDCs decision last month to roll back its mask guidance and encourage even vaccinated people to wear them in areas of the country with high rates of transmission.

Another study published Tuesday in the same MMWR issue indicated that from May through July in Los Angeles County, unvaccinated people had five times the rate of Covid-19 infections as vaccinated people and were 29 times more likely to be hospitalized.

If Vaccines Stop Covid Spread What Does That Mean For Us

The best-case scenario is the COVID-19 vaccines completely stop transmission, and once we get enough of the population vaccinated, the virus has no-one left to infect and tapers off to nothing.

Sounds great, doesn’t it?

“If we do have vaccines that allow prevention of transmission, this really does change the game in terms of our international travel, our lockdowns and the way we think about the virus,” Professor McMillan says.

If we could eliminate the virus completely, we would not have to worry about updating future vaccines to shield us from new COVID variants that may evolve to elude current jabs, Dr Labzin says.

“But it’s pretty hard to do. Even though we’ve had all these vaccines for different things for many years, smallpox is the only one we’ve managed so far,” she says.

“It just goes to show that’s a really huge goal and it’s probably not necessarily achievable .”

Besides, it is highly unlikely any of our current crop of COVID-19 vaccines will provide sterilising immunity.

While early trials showed the vaccines reduced the amount of virus in animals’ lungs, none of the jabs completely eliminated it from their system, Professor Lewin says.

“I think it’s because it’s so easy to infect the nose there are so many receptors for the virus there,” she says.

“But next-generation vaccines may well induce sterilising immunity.”

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What We Are Still Learning

  • How well the vaccines protect people with weakened immune systems, including people who take medicines that suppress the immune system
  • How long COVID-19 vaccines protect people
  • How many people have to be vaccinated against COVID-19 before the population can be considered protected
  • How effective the vaccines are against new variants of the virus that causes COVID-19

I Have A Weakened Immune System Do I Need A Third Dose Of The Covid

Early research shows Pfizer vaccine could prevent COVID-19 transmission

In August 2021, the FDA authorized a third dose of an mRNA vaccine for certain people who are immunocompromised. The third dose should be given at least 28 days after the second dose.

The COVID-19 vaccines, like other vaccines, work by stimulating a persons immune system to produce antibodies against the virus. If the antibodies later encounter the actual virus, they are ready to recognize and destroy it.

A person with a weakened immune system may not be able to produce a strong enough immune response to the standard, two-dose COVID mRNA vaccine regimen. This leaves them more likely to have a breakthrough infection, and increases the risk of more severe disease if they do become infected. A third vaccine dose may enhance the immune response in some people who are immunocompromised.

The FDA authorized a third dose for people who are moderately to severely immunocompromised. A person may have a weakened immune system for a variety of reasons. These include being born with an immunodeficiency, having advanced or untreated HIV, and having a chronic medical condition such as chronic kidney disease or lack of a spleen. Many types of medication also suppress the immune response, including some cancer treatments, TNF blockers, some biologic agents, and high-dose corticosteroids. Talk to your doctor if you think you may qualify for a third COVID vaccine dose.

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Could An Mrna Vaccine Change My Dna

An mRNA vaccine the first COVID-19 vaccine to be granted emergency use authorization and then full approval by the FDA cannot change your DNA.

mRNA, or messenger RNA, is genetic material that contains instructions for making proteins. mRNA vaccines for COVID-19 contain man-made mRNA. Inside the body, the mRNA enters human cells and instructs them to produce the “spike” protein found on the surface of the COVID-19 virus. Soon after a cell makes the spike protein, the cell breaks down the mRNA into harmless pieces. At no point does the mRNA enter the cell’s nucleus, which is where our genetic material lives.

The immune system recognizes the spike protein as an invader and produces antibodies against it. If the antibodies later encounter the actual virus, they are ready to recognize and destroy it before it causes illness.

Q: Does The Fda Foresee Any Instance In Which A Vaccine Might Receive An Eua And Not Meet The Criteria For A Biologics License Application If A Product Doesnt Meet The Bla Standard Does The Eua Get Revoked

A: If safety or effectiveness concerns arise with a vaccine under EUA, the FDA has the authority to revoke the EUA. However, it is expected that the data supporting the EUA, together with those that will be collected during use of vaccine under EUA, and additional data collected from ongoing trials will be sufficient to support licensure of a vaccine authorized under EUA.

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Reassurance For Public Policymakers

“I think it reassures the public and the policymakers that the current vaccines are highly effective in a real-world, high-risk population,” Butt says about the significance of the findings.

It should also allay concerns about mRNA technology in its new use for vaccines, he says.

Next, the researchers will look at specific populations that may be highly vulnerable, such as people on hemodialysis, he says.

“We know from early studies that people on dialysis have less robust immune response to vaccines,” Butt says. “Now, whether that translates to less effectiveness of vaccines remains to be seen, and thatââ¬â¢s what we are studying. That paper is in peer review right now.”

He says the two biggest challenges in translating their research into practice are “overcoming vaccine skepticism and hesitancy, and ensuring global equity in distribution, whereby the most vulnerable from the poorest nations also have equitable access to these highly effective vaccines.”

The Vaccines Can Be Updated To Be More Effective

Fauci: Early COVID

Research continues on all the vaccines. If necessary, future COVID-19 vaccines may need to be tweaked, not unlike what happens with the flu vaccine every year. All vaccine manufacturers are continuing to study the effectiveness of the vaccines and are already looking at what a booster might look like down the road.

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From: Caitlin Smithoctober 07 2021

Dear Ministry of Health,

On the Medsafe website it states that there is limited information available on the safety of the Comirnaty vaccine for pregnant women. As I understand it the Pfizer clinical trials have not been completed for use of the Comirnaty vaccine in pregnant and breastfeeding women. Yet the Ministry of Health website states that the vaccine is safe for pregnant and breastfeeding women:

Why is there contradictory information being provided here? How can the Ministry of Health State that the covid vaccine is safe for pregnant and breastfeeding women when the Medsafe website states that there is limited information on the safety of the vaccine for pregnant women? Where is the Ministry of Health of getting the data from for clinical trials on pregnant and breastfeeding women? Has the FDA approved the use of the Pfizer covid vaccine for use in pregnant and breastfeeding women? Please could you provide the safety data, including clinical trial data collected in New Zealand and overseas that proves the safety of and authorisation for use of the Pfizer covid vaccine in pregnant and breastfeeding women?

Yours faithfully,

Catching And Passing On Covid

The Pfizer vaccine is effective at reducing the number of people who get COVID-19.

Its harder to find out how well the vaccine stops people passing on the COVID-19 virus. Recent studies show that the Pfizer vaccine can reduce transmission of the virus. These studies looked at the number of people infected with COVID-19 after theyd been vaccinated and their close contacts.

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How Long Will It Protect Me Will I Have To Get A Covid

This is a question researchers are eager to answer. People who are infected with the coronavirus show a decline in protection within a few months, but their immunity may last significantly longer than that. . Data from the vaccine trials indicate strong immunity at least months after vaccination, indicating possible long-term immunity.

As the SARS-CoV-2 coronavirus has begun to change , studies are exploring how these changes affect the viruss characteristics, including its ability to spread between people. A substantial mutation might have an impact on the effectiveness of the vaccines, and vaccine manufacturers are preparing to make adjustments where necessary.

What Do We Know About The Moderna Covid

Pfizer CEO: Death prevention is the most important COVID-19 vaccine efficacy measure

On December 18, 2020, the FDA granted emergency use authorization to an mRNA COVID-19 vaccine developed by Moderna in collaboration with scientists from the NIH. The vaccine is approved for use in people 18 years and older. This is the second COVID-19 vaccine authorized for use in the US.

The FDA granted EUA based on their own analysis of efficacy and safety data, as well as on the recommendation made by the Vaccines and Related Biological Products Advisory Committee . VRBPAC is a group of outside experts in infectious disease, vaccinology, microbiology, immunology, and other related fields.

In briefing documents submitted to the FDA, the Moderna vaccine showed an overall efficacy of 94.1% in preventing COVID-19. This study enrolled 30,400 adults half received the vaccine, half received a saltwater placebo shot. There were 196 infections among the study participants. Of these, 185 were in the placebo group and 11 were in the vaccine group. All 30 cases of severe COVID occurred in the placebo group, strongly suggesting indicating that the vaccine reduces risk of severe illness.

The vaccine was similarly effective in people older and younger than 65, in men and women, in people with and without medical conditions that put them at high risk for severe illness, and in different racial and ethnic groups.

The most common vaccine side effects were pain at the injection site, fatigue, headache, muscle pain, joint pain, and chills.

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Is There A Vaccine For The Coronavirus Disease

Several COVID-19 vaccines have been authorized for emergency use among specific age groups by the U.S. Food and Drug Administration . Johns Hopkins Medicine views all authorized COVID-19 vaccines as highly effective at preventing serious disease, hospitalization, and death from COVID-19.

Learn more about coronavirus vaccine safety and what you need to know about the COVID vaccines.

Are There Any Groups Of People Who Should Not Get The Mrna Covid

There are only a few groups of people who should not get the mRNA vaccine. They include people who

  • are allergic to any components of the mRNA vaccine, which include polyethylene glycol and polysorbate
  • had an allergic reaction within the first 30 minutes after receiving the first dose of an mRNA COVID-19 vaccine.

If you have a history of allergic reactions to other vaccines or to injectable medications, ask your doctor if it is safe for you to get one of the currently available mRNA vaccines.

Finally, it is possible that convalescent plasma or monoclonal antibodies, both of which are used to treat COVID-19, could reduce the effectiveness of the vaccine. If you have received either of these treatments, wait 90 days before getting your vaccine.

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