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Updated on July 1, 2022 1:32 pm
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Updated on July 1, 2022 1:32 pm
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Updated on July 1, 2022 1:32 pm

Global Statistics

All countries
Updated on July 1, 2022 1:32 pm
All countries
Updated on July 1, 2022 1:32 pm
All countries
Updated on July 1, 2022 1:32 pm
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How Long Do Side Effects Last After Second Covid Vaccine

Clinical Contributors To This Story

Many report side effects after second COVID-19 vaccine dose

Thomas Bader, M.D. contributes to topics such as Medical Quality.

After hearing how some of your friends have fared when they got the COVID-19 vaccine, are you wondering how youll feel once you receive the shot? Some people experience flu-like symptoms. Others feel discomfort at the injection site. Still others dont notice anything at all. Its impossible to know what side effects you may experience until you get vaccinated, but symptoms typically disappear within a few days.

Here are answers to questions that you may have about COVID-19 vaccine side effects:

When To Call The Doctor

In most cases, discomfort from pain or fever is a normal sign that your body is building protection. Contact your doctor or healthcare provider:

  • If the redness or tenderness where you got the shot gets worse after 24 hours
  • If your side effects are worrying you or do not seem to be going away after a few days

If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911. Learn more about COVID-19 vaccines and rare severe allergic reactions.

Pfizer Vaccine Side Effects

People who get the Pfizer COVID-19 vaccine will likely experience soreness, redness and swelling at the injection site, and potentially chills and fatigue. The Food and Drug Administration lists a couple of additional side effects for the Pfizer-BioNTech vaccine specifically, including muscle pain, joint pain, nausea and swollen lymph nodes.

The FDA notes that most people experienced these side effects after the second dose of the vaccine.

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What This Means For You

You cannot get infected with the SARS-CoV-2 virus from a COVID-19 vaccine. The side effects that you might experience are just a sign that your body’s immune system is responding.

However, if your side effectslike fever and body achesdo not get better within 72 hours of getting your shot, or they get worse, you should get tested for COVID-19. It’s possible that you caught the virus around the same time that you got your shot or in between doses.

The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit our coronavirus news page.

Fever After Vaccination Against Covid

What to expect after a COVID

If you develop a fever within 48 hours after receiving the vaccination, it is likely that the fever is a side-effect of the vaccination. In that case, it is best to stay home yourself, but your household members do not have to stay home. If you have a fever, but also have other symptoms that could indicate COVID-19, such as cold symptoms, coughing, or sudden loss of smell or taste, make an appointment to get tested. Except for the test, you must stay home, and your household members must also stay home until you get the results of the test. In case of doubt, you can consult the GGD infectious disease control department. If you develop a fever more than 48 hours after vaccination, you may have a coronavirus infection. In that case, get tested you and your household members must stay home until you get the results of the test.

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Potential Side Effects After Taking Covid

Image Source: Pexels

Some of the more common side effects of the Covid-19 vaccine include the following:

  • Pain

  • Fever

  • Nausea

The HSA says that the reactions can possibly be associated with the vaccination but may not have been caused by it. Healthcare providers reported to the HSA saying that any undesirable medical condition which occurs after taking the vaccine does not necessarily have a direct link to the treatment.

It may be coincidental or related to undiagnosed disease.

When Youre Likely To Experience A Side Effect

Most side effects show within a day or two after being vaccinated.

What you may feelWhat can helpWhen this could start

Pain at the injection site, a headache and feeling tired and fatigued. These are the most commonly reported side effects.

Place a cold, wet cloth, or ice pack on the injection site for a short time.

Do not rub or massage the injection site.

Within 6 to 24 hours

Muscle aches, feeling generally unwell, chills, fever, joint pain and nausea may also occur.

Rest and drink plenty of fluids

Paracetamol or ibuprofen can be taken, follow the manufacturers instructions.

Seek advice from your health professional if your symptoms worsen.

Within 6 to 48 hours

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What Are The Potential Side Effects

Side effects are possible after receiving any COVID vaccine currently being administered in the U.S.

Experiencing side effects isn’t necessarily a bad thing. In fact, it’s a sign your body is responding and the vaccine is working.

According to Pfizer, about 3.8% of their clinical trial participants experienced fatigue as a side effect and 2% got a headache.

Moderna says 9.7% of their participants felt fatigued and 4.5% got a headache.

The CDC reports the most common side effects for the vaccines is at the injection site. They include:

  • Pain

Coronavirus Disease : Vaccines Safety

Understanding COVID-19 vaccine side effects, why second dose could feel worse

English version is updated on 29 July 2021 – Information about COVID-19 vaccines is quickly evolving and WHO will aim to update this Q& A on an ongoing basis, as we learn more.

There are strict protections in place to help ensure the safety of all COVID-19 vaccines. Before receiving validation from WHO and national regulatory agencies, COVID-19 vaccines must undergo rigorous testing in clinical trials to prove that they meet internationally agreed benchmarks for safety and efficacy.

Unprecedented scientific collaborations have allowed COVID-19 vaccine research, development, and authorizations to be completed in record time to meet the urgent need for these vaccines while maintaining high safety standards. As with all vaccines, WHO and regulatory authorities will continuously monitor the use of COVID-19 vaccines to identify and respond to any safety issues that might arise, and through that process to assure they remain safe for use around the world.

Reported side effects to COVID-19 vaccines have mostly been mild to moderate and short-lasting. They include: fever, fatigue, headache, muscle pain, chills, diarrhoea, and pain at the injection site. The chances of any of these side effects following vaccination differ according to the specific COVID-19 vaccine.

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Are There Special Side Effects To Be Aware Of From The Johnson & Johnson Viral Vector Vaccine

As part of the normal safety surveillance of all new medications, the Food and Drug Administration and Centers for Disease Control and Prevention tracks recipients for any unusual medical conditions. In April, the FDA placed a pause on the Johnson & Johnson / Janssen vaccine, after serious blood clots were identified in six people .

All of the people who experienced this side effect were women between the ages of 18 and 48, who noticed symptoms between six and 13 days after they were vaccinated. After a thorough review of the cases, the FDA decided to resume use of the Johnson & Johnson / Janssen vaccine shortly after the pause.

The FDA did add the recommendation that if you notice any of the following symptoms in the first two weeks after you receive the Johnson & Johnson / Janssen vaccine, you should seek medical care right away:

  • severe headaches
  • swelling or pain in the legs
  • trouble breathing, or shortness of breath
  • bruising easily

My Side Effects Are Not Going Awaycould I Have Covid

In some cases, you might get your COVID-19 shot around the same time that you have been exposed to the virus. If this happens, you could develop symptoms of COVID-19in which case you would be capable of spreading it to others.

Some people by chance may become infected with coronavirus between their first and second dose before they are fully immune, DSouza says. It takes several days after infection for symptoms to develop so they might get their second dose.

Common side effects of the vaccine, like fatigue, fever, or body aches, can also occur if you have a COVID-19 infection. The way to tell the difference is by the timing and severity of your symptoms. If you don’t start to feel better within a few days of getting your shot, or your side effects are getting worse, you should get tested for COVID-19.

If your symptoms last longer than 72 hours, it is worth making sure you dont actually have COVID-19, Juthani says. If you do, you didnt get it from the vaccine, you just happened to get it from someone else around the time you got your vaccine.

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Reports Of Very Rare Blood Clots

The MHRA is carrying out a detailed review of reports of a very rare blood clotting problem affecting a small number of people who have had the Oxford/AstraZeneca vaccine.

The problem can also happen in people who have not been vaccinated and it’s not yet clear why it affects some people.

The current reported rate of this condition in the UK is around 15 cases per million first doses given.

The coronavirus vaccine can help stop you from getting seriously ill or dying from coronavirus. For people aged 40 or over and those with underlying health conditions, the benefits of being vaccinated outweigh any risk of clotting problems.

For people under 40 without underlying health conditions, it’s currently advised that it’s preferable to have another coronavirus vaccine instead of the Oxford/AstraZeneca vaccine.

If you have already had a first dose of the Oxford/AstraZeneca vaccine without suffering any serious side effects you should complete the course .

This includes people aged 18 to 39 years who are health and social care workers, unpaid carers and household contacts of those who are severely immunosuppressed.

What If You Get Infected Before Your Second Shot


Landstrom and Varner both stress that vaccines are not given to active COVID-19 patients. If a person is infected with COVID-19 before the second COVID-19 shot, Varner says that it could be at least two weeks before a person can get the second dose. It is recommended that you wait until after youve cleared your infection, Varner says.

While unexpected events can happen, Varner suggests people still schedule their second vaccine appointment ahead of time. “I would recommend they schedule that second vaccine while they’re getting the first one,” Varner says.

As more information about the vaccines and the duration of immunity unfolds, Landstrom stresses the importance of continuing to maintain COVID-19 safety practices.

It is important to continue to do those things that we have done through the pandemic,” Landstrom says. “So even with the vaccine, while it is very effective, it is not 100% effective. And so adding the physical distancing, the washing of hands, the wearing of masks, really help protect people further.”

The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit our coronavirus news page.

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So Should I Worry If They Are On The Same Day

In short, no.

The study found no significant differences between receiving the jabs on the same day and getting them 34 weeks apart.

The timing of the jabs also had no major effect on antibody response to either vaccine.

The team presented the results of the study to the U.K. Joint Committee on Vaccination and Immunisation, ultimately shaping the countrys fall and winter plan.

The committee later issued advice saying that the coadministration of the flu vaccine with a booster or second dose of a COVID-19 vaccine is fine.

And although health bodies will not recommend that everyone should get both vaccines on the same day, both the CDC and NHS say that this approach is safe and convenient.

It is best to get vaccinated for both of these serious respiratory infections this year than not get vaccinated at all, so go ahead and get them at the same time. You are unlikely to have worse adverse effects and should have a good reaction to both.

Dr. Monica Gandhi

Getting both vaccines on the same day could also have a practical benefit for healthcare administrators.

Warning: Second Dose Of Covid

CLEVELAND, Ohio – After receiving the second dose of the COVID-19 vaccine, many are reporting side effects that were more severe than after the first dose.

I kept hearing, well, the second shot is gonna be a little tougher, said RN Mario Becerra. I said, oh really well, what does that mean?

Becerra works in a local hospital and just received his second dose of the COVID-19 vaccine, and less than 24 hours later, Mario was hit with a whirlwind of side effects.

I had some chills last night, a headache, the injection sight hurt like a bear, said Becerra. Im not kidding if youve ever had a tetanus shot it was similar to that it was really, really sore.

University Hospitals, Director of Infection Control, Claudia Hoyen tells me what Becerra experienced is very common.

Those are caused by your immune system and some of the chemicals that get released when youre trying to quote on quote fight something off, said Hoyen.

If you or your loved ones are feeling crummy after getting your second shot, or even after your first, dont panic. Its just your bodys way of creating immunity Its the one time where feeling bad is technically a good thing.

When I woke up and could feel some chills, I was like, okay, its working, said Becerra. Im not getting hit as hard its doing what it has to do, thats good.

Health professionals say getting side effects, in this case, is similar to when you get the flu shot.

Here are the side effects people have reported by the FDA.

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What Do The Side Effects Mean

If you get side effects, they are a good sign they indicate that the vaccine is working by triggering the immune system.

When you get the first shot, your immune system recognizes something as being foreign. The immune system automatically launches a small-scale attack against it. This process teaches your immune cells to recognize and respond to an invader. Thats why you might experience some side effects.

When you get the second shot, your immune system launches that attack again. But this time, there are more immune cells ready and waiting to launch a much bigger assault. Thats why you might feel more side effects after the second dose. But they will disappear after a day or two. Think of it this way: The bodys response to the vaccine is like a training mission for the real fight.

Once youre fully vaccinated, if you were infected by the virus causing COVID-19, your immune system would be ready to launch an even larger and more powerful attack to protect you.

If you dont experience any side effects from either the first or second dose that doesnt mean that the vaccine didnt work. In the vaccine clinical trials, more than half of people didnt experience any side effects but we still know that the vaccine was effective in those people.

General Vaccine Side Effects

What Are the Long-term Side Effects of COVID-19 Vaccine?

All vaccines have possible side effects with mild to moderate severity. Typical vaccine side effects include local pain, swelling, redness and sometimes bruising at the injection site, as well as fever and tiredness, says Dr. Roshni Mathew, pediatric infectious diseases physician at Stanford Children’s Health.

With any vaccination, you can expect a bit of pain during and after the injection, says Dr. Thomas Duszynski, director of epidemiology education at Indiana University. He adds that some people may experience chills, fatigue or minor headaches after vaccines.

Sandra Lindsay, a nurse at Long Island Jewish Medical Center, is inoculated with the COVID-19 vaccine.

According to the Centers for Disease Control and Prevention, common COVID-19 vaccine side effects include:

  • Injection site pain
  • Tiredness

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Managing Common Side Effects At Home

You can take over-the-counter medicine after your vaccination to help with any pain or to lower a fever. Ask your health care provider how to manage any symptoms and if you’re concerned about any symptoms post-vaccination.

You can also:

  • apply a clean, cool, wet washcloth over the area you received the injection
  • use or exercise your arm
  • drink plenty of fluids

Table 4 Systemic Reactions In Persons Aged > 55 Years Pfizer

Table 4. Systemic reactions in persons aged > 55 years, Pfizer-BioNTech COVID-19 vaccine and Placebo

Dose 1

a Mild: does not interfere with activity moderate: some interference with activity severe: prevents daily activity Grade 4: emergency room visit or hospitalization for severe fatigue, severe headache, severe muscle pain, or severe joint pain.

b Mild: 1 to 2 times in 24 hours moderate: > 2 times in 24 hours severe: requires intravenous hydration Grade 4: emergency room visit or hospitalization for severe vomiting.

c Mild: 2 to 3 loose stools in 24 hours moderate: 4 to 5 loose stools in 24 hours severe: 6 or more loose stools in 24 hours Grade 4: emergency room visit or hospitalization for severe diarrhea.

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What Are The Covid

According to the Centers for Disease Control and Prevention , there are several side effects of the COVID-19 vaccines that are relatively common. If you experience these side effects they are usually not serious and go away on their own in a short time:

Severe reactions to the COVID vaccine usually occur within 15 minutes of getting the shot. That’s why most vaccination sites ask you to stick around for 15 minutes to a half-hour after you get your dose to monitor you.

If youve had a history of anaphylaxis, you should be observed for 30 minutes to make sure that you dont develop another such episode, Manisha Juthani, MD, infectious diseases specialist at Yale Medicine and associate professor at the Yale School of Medicine, tells Verywell. For symptoms that develop after the initial vaccination period, if you have symptoms that last more than 72 hours after your vaccine, you should call your doctor. If you develop a rash at the site of the vaccination, you could have a local allergic reaction.

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