Global Statistics

All countries
Updated on July 4, 2022 7:56 am
All countries
Updated on July 4, 2022 7:56 am
All countries
Updated on July 4, 2022 7:56 am

Global Statistics

All countries
Updated on July 4, 2022 7:56 am
All countries
Updated on July 4, 2022 7:56 am
All countries
Updated on July 4, 2022 7:56 am
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How Many Weeks Between Covid Vaccines

How You Will Get The Coronavirus Vaccine

How long should you wait to get the COVID-19 vaccine after getting a pneumonia shot?

For most people, the vaccination journey happens in 4 stages:

  • receiving an invitation for your first dose
  • attending your first vaccination appointment
  • receiving an invitation for your second dose
  • attending your second vaccination appointment

You need to get all the recommended doses of the coronavirus vaccine for maximum protection. The second dose gives you more and longer-term protection against the coronavirus variants that are currently causing concern, including the highly transmissible Delta variant.

People aged 12 and over who are severely immunosuppressed are now eligible for a third dose of the coronavirus vaccine. Your clinician will decide if you should receive a third dose. There’s no need for you to take any action – your health board will contact you to arrange an appointment.

New And Emerging Research Priorities

Efficacy, effectiveness, immunogenicity and safety

  • What is the population effectiveness and medium and long-term durability of protection of a single dose or a complete series of each COVID-19 vaccine approved in Canada?
  • What is the efficacy, effectiveness, immunogenicity, and safety of COVID-19 vaccines across diverse population groups ? Is a third booster dose of vaccine or a higher dose of vaccine needed to elicit an appropriate immune response in these individuals?
  • What is the efficacy, effectiveness, immunogenicity and safety of COVID-19 vaccines in individuals who have had a previous laboratory evidence of SARS-CoV-2 infection?
  • Is there a discernable difference between seronegative and seropositive people in any of the above parameters?
  • Does previous exposure to SARS-COV-2 impact efficacy, effectiveness, immunogenicity or safety of COVID-19 vaccines?
  • Can a single-dose vaccine series be as effective and safe in individuals with previously proven COVID-19 disease?
  • Are there any emerging safety signals with COVID-19 immunization that are not predicted by the current understanding of the safety profile of similar vaccines?
  • Does vaccination following prior SARS-CoV-2 infection or vaccination of SARS-CoV-2 naïve individuals elicit enhanced or altered disease upon subsequent infection by SARS-CoV-2 or other endemic coronaviruses?
  • What is the efficacy, effectiveness, immunogenicity and safety of COVID-19 vaccines against SARS-CoV-2 variants of concern?
  • Vaccine administration

    Whats The Recommended Dosage

    SAGE recommends the use of BIBP vaccine as 2 doses given intramuscularly. WHO recommends an interval of 34 weeks between the first and second dose. If the second dose is administered less than 3 weeks after the first, the dose does not need to be repeated. If administration of the second dose is delayed beyond 4 weeks, it should be given at the earliest possible opportunity. It is recommended that all vaccinated individuals receive two doses.

    Recommended Reading: Can 14 Year Olds Get Covid Vaccine

    Appendix D: Clinical Trial Evidence Summary For Janssen Covid

    Data from Phase 1, 2, and 3 trials were available at the time of authorization for the Janssen vaccine. Evidence on efficacy, immunogenicity, and safety is available for adults â¥18 years of age. The Phase 3 trial involved 44,325 study participants randomized to receive either the vaccine or placebo. The data presented below was a median of two months after the completion of the series . Evidence from post-marketing surveillance and studies is found in the main body of this statement.

    How Long Can You Wait Between Covid

    N.B. COVID

    The United Kingdom Chief Medical Officers have said that the second dose of the Covid-19 … vaccines can be given up to 12 weeks following the first dose. But not everyone agrees.

    So youve already gotten your first dose of the Covid-19 vaccine. And now you wondering when you can get the…wait for it, wait for it…second dose of the Covid-19 vaccine.

    The official answer may be 21 days after the first dose for the Pfizer/BioNTech Covid-19 vaccine, 28 days after the first dose for the Moderna vaccine, and 28 days or more after the first dose of the Oxford-AstraZeneca vaccine. But how exact are these time limits? Is this like Baby Groot deciding when to trigger the bomb in Guardians of the Galaxy 2 or microwaving a Hot Pocket, where even small excursions from the recommended time limit can lead to disaster? Are the 21-day or roughly two Scaramucci interval for the Pfizer/BioNTech Covid-19 vaccine and the 28-day or nearly three Sacaramucci interval for the Moderna and Oxford-AstraZeneca vaccines set in stone? Or are they more set in avocado mash? Is there some leeway? If so, by how much?

    It turns out that there is some leeway. You wait a little longer to receive the second dose of the vaccine. The question right now is whether the leeway is up to six weeks or even longer, up to 12 weeks . And whether this leeway may vary by vaccine. But more on that later.

    Vaccine supply issues may determine when you are actually able to get the second dose of the … Covid-19 vaccine.

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    How The Study Worked

    To assess the efficacy of a delayed second dose or a third dose, researchers vaccinated volunteers aged 1855 years who were enrolled in a clinical trial of the AstraZeneca vaccine and had already received either one or two doses.

    In total, 30 participants received a late second dose at a median of 44 weeks after the first. The scientists found that their subsequent antibody levels were higher than those who received their second dose after shorter dose intervals.

    In 90 participants who received a third dose, antibody levels were higher compared with the antibody response 28 days after a second dose. Their T cell immune responses also received a boost.

    Volunteers experienced less reactogenicity to the vaccine after a delayed second or a third dose compared with the first dose.

    However, the authors note some shortcomings of their study. For example, there was limited data on T cell responses after a delayed second dose.

    In addition, they only measured immune responses up to 28 days after a third dose. But, they plan to follow up with volunteers at 6 months.

    Finally, the current research only included younger adults, but a study of older adults is already underway.

    For live updates on the latest developments regarding the novel coronavirus and COVID-19, click here.

    You Can Wait Longer Than Three Weeks

    The Australian Technical Advisory Group on Immunisation recommends a minimum of three weeks between the first and second Pfizer dose. However it says this gap can be extended to up to six weeks.

    The minimum time to establish immune memory following first exposure to a new vaccine is roughly three weeks. This is the minimum time, but waiting longer between the first and second jab is absolutely fine in terms of efficacy.

    This makes sense based on what immunology experts understand about our immune response to vaccines.

    At this stage, some of these become memory immune cells, and by about the third week they have established immune memory. This means these virus-recognising cells are on hand to rapidly respond if we are exposed again.

    If that exposure is via a second immunisation, this will boost the immune response to the vaccine and increase immune memory, which in turn enhances protection against the virus.

    Read more:How long do COVID vaccines take to start working?

    The secondary immune response is faster and bigger because you have a pool of memory immune cells primed and ready to jump into action. The memory response is also faster, so by two weeks after the second jab, protection has significantly increased.

    Youre not fully protected against COVID until about seven to 14 days after the second Pfizer dose.

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    Its Important To Continue Masking Up And Maintaining Social Distance

    Again, even after youve been fully immunized, vaccine breakthroughs are expected. That is one reason why some recommendations for fully vaccinated individuals have changed , while others have not budged.

    Its still important for everyone to mask up and maintain social distance. If youre vaccinated, you should still be doing these things unless youre in a private place with other vaccinated individuals or one other low-risk, unvaccinated household. If youre not yet vaccinated, get whatever vaccine is available to you, whenever its available to you.

    Were learning more and more that the vaccines also are preventing transmission, so not only are you protecting yourself, but youre protecting others, Cluzet said. Its personal health, but its also public health.

    Why We Need T

    Singapore to extend interval between COVID-19 vaccine doses to up to 8 weeks

    After the second dose, a wider gap also resulted in higher neutralising antibody levels against the Delta variant and all other variants of concern, they found. But in this instance, antibody levels dropped off between first and second dose leaving the recipients vulnerable against the Delta variant after one jab.

    Dr Rebecca Payne, one of the studys authors from Newcastle University, said the cellular response from infection-fighting T cells remained consistent across both long and short dosing gaps, suggesting they play an important role in protecting against Covid-19 between the first and second jab.

    After the second dose on the longer dosing schedule, antibody levels surpassed those seen at the same timepoint after a shorter dosing interval, she added. Although T cell levels were comparatively lower, the profile of T cells present suggested more support of immune memory and antibody generation.

    Researchers said there may be exceptions where the gap between doses may need to be shortened from eight weeks to four, such as before treatments that may affect the immune system, such as cancer or organ transplant.

    Vaccines minister Nadhim Zahawi said the government took the JCVIs advice to shorten the dosing interval from 12 to eight weeks to help protect more people against the Delta variant.

    This latest study provides further evidence that this interval results in a strong immune response and supports our decision, he added.

    Read Also: How To Prepare For Covid Vaccine

    Which Vaccine Will I Get

    You cannot usually choose which vaccine you have. When you book, you’ll only be offered appointments for vaccines that are suitable for you.

    Most people can have any of the COVID-19 vaccines, but some people are only offered certain vaccines.

    For example:

    • if you’re pregnant or under 40 you’ll usually be offered appointments for the Pfizer/BioNTech or Moderna vaccines
    • if you’re under 18, you’ll only be offered the Pfizer/BioNTech vaccine

    You should have the same vaccine for both doses, unless you had serious side effects after your 1st dose.

    Vaccine Review Approval And Monitoring

    Health Canada’s independent drug review process is recognized around the world for its high standards and rigor. Our decisions are based only on scientific and medical evidence showing that vaccines are safe and effective. The benefits must also outweigh any risks.

    Find detailed technical information such as the product monograph and the regulatory decision summary:

    As COVID-19 vaccines are administered across Canada, our safety monitoring is ongoing. The Public Health Agency of Canada, Health Canada, and provincial and territorial health authorities continue to:

    • monitor the use of all COVID-19 vaccines closely
    • examine and assess any new safety concerns

    Also Check: How Do Most People Get Covid

    How Much Time To Leave Between Your Two Pfizer Vaccine Doses

    Leaving eight weeks between your first and second dose of the Pfizer Covid-19 vaccine is the optimum gap for immunity and protection, say scientists.

    A new study, funded by the Department of Health and Social Care has found that a 10-week gap between doses produces higher antibody levels, as well as a higher proportion of infection-fighting T cells, compared to just four weeks.

    However, scientists involved in the study have described an eight-week dosing interval as the sweet spot when it comes to generating a strong immune response while also protecting the UK population against the Delta variant of coronavirus to which people can still be vulnerable after just one jab.

    Appendix C: Clinical Trial Evidence Summary For Astrazeneca Covid

    Moderna Coronavirus Vaccine Arrives In NYC: 25K Doses So Far

    Results from four clinical trials were available at time of authorization for the AstraZeneca COVID-19 vaccine. Results from an ongoing Phase 3 trial in the United States were not available at time of writing. Evidence on efficacy, immunogenicity, and safety is available for adults â¥18 years of age. The Phase 2/3 trial trial and Phase 3 trial assessed efficacy, safety and immunogenicity of the vaccine. The Phase 2/3 trial was based in the United Kingdom, while the Phase 3 trial was based in Brazil. These two studies underwent a series of protocol amendments and logistical challenges during the conduct of the trials that resulted in significant changes to the trials’ methodology. There were changes from a single to a two-dose vaccine regimen, the use of both a low dose/standard dose and standard dose/standard dose vaccine regimen, and the recruitment of progressively older study participants after the initial focus on adults 18-55 years of age. In the SD/SD vaccine regimen, study participants were randomized to receive either the AstraZeneca COVID-19 vaccine, AZD1222 or control injection. The participants randomized to the control group were administered two doses of quadrivalent meningococcal vaccine or MenACWY for Dose 1 and placebo for Dose 2 .

    Evidence from the AstraZeneca COVID-19 vaccine trials has been publishedFootnote 150. Evidence from post-marketing surveillance and studies is found in the main body of this statement.

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    Vaccination Card And Your Second Shot

    At your first vaccination appointment, you should have received a vaccination card that tells you what COVID-19 vaccine you received, the date you received it, and where you received it. Bring this vaccination card to your second vaccination appointment.

    • If you did not receive a COVID-19 vaccination card at your first appointment, contact the vaccination provider site where you got your first shot or your state health department to find out how you can get a card.
    • If you have lost your vaccination card or dont have a copy, contact your vaccination provider directly to access your vaccination record.
    • If you cannot contact your vaccination provider directly, contact your state health departments immunization information system . You can find state IIS information on the CDC website. Vaccination providers are required to report COVID-19 vaccinations to their IIS and related systems.
    • If you enrolled in v-safe or VaxText after your first vaccine dose, you can access your vaccination information using those tools.
    • If you have made every effort to locate your vaccination information, are unable to get a copy or replacement of your vaccination card, and still need a second shot, talk to a vaccination provider.
  • Bring your vaccination card with you to your second shot appointment so your provider can fill in the information about your second dose.
  • Does It Prevent Infection And Transmission

    There is currently no substantive data available related to the impact of COVID-19 vaccine BIBP on transmission of SARS-CoV-2, the virus that causes COVID-19 disease.

    In the meantime, WHO reminds of the need to maintain and strengthen public health measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds and ensuring adequate ventilation.

    Read Also: How Accurate Are Covid Swab Tests

    Timing Of Your Second Shot

    The timing between your first and second shots depends on which vaccine you received. If you received the:

    Moderna COVID-19 vaccineGet your second;shot 4 weeks after your first

    People with moderately to severely compromised immune systems should receive an additional dose;of mRNA COVID-19 vaccine after the initial 2 doses.

    You should;get your second shot as close to the recommended 3-week or 4-week interval as possible. However, your second dose may be given up to 6 weeks after the first dose, if necessary. You should not get the second dose early. There is currently limited information on the effectiveness of receiving your second shot earlier than recommended or later than 6 weeks after the first shot.

    However, if you do receive your second shot of COVID-19 vaccine earlier or later than recommended, you do not have to restart the vaccine series. This guidance might be updated as more information becomes available.

    Cases of myocarditis and pericarditis in adolescents and young adults have been reported more often after getting the second dose than after the first dose of one of the two mRNA COVID-19 vaccines, Pfizer-BioNTech or Moderna.;These reports are rare and the known and potential benefits of COVID-19 vaccination outweigh the known and potential risks, including the;possible risk of myocarditis or pericarditis.

    How Long Should I Wait To Receive My Second Dose

    How are the Pfizer and Moderna COVID-19 vaccines different?

    The Joint Committee on Vaccination and Immunisation currently advises a minimum gap of eight weeks between first and second doses;for the Pfizer/BioNTech and AstraZeneca vaccines, based on evidence that this interval is best in boosting immunity against the Delta variant.

    Until May, the Government had imposed a 12-week gap between doses, in order to prioritise first doses for as many people as possible with limited vaccine supplies.

    However, the minimum gap between doses was shortened to eight weeks in May following growing concerns of the Delta variant.

    While some other countries are offering second jabs after three weeks, there is some evidence that waiting longer between doses can make vaccines more effective. A study funded by the Department of Health and Social Care , found that compared to a four-week gap, a 10-week interval between doses produces higher antibody levels.

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    Is There A Sweet Spot

    While research shows the AstraZeneca jab generates the strongest immune response when given 12 weeks apart, Professor Nolan said reducing that interval to eight weeks only reduced that protection modestly.

    “There’s actually a curve that shows the optimisation of protection as you get to 12 weeks,” he said.

    “The data shows that if you do move things back to say, eight weeks, it’s not a huge amount that you lose.”

    Kylie Quinn, a vaccine expert at RMIT, agreed that giving the AstraZeneca jab at eight weeks still provided “pretty decent levels of protection”.

    But she said any decision to reduce the recommended interval between vaccines should be based on what a country’s goal is.

    If building the highest protection possible in every individual is top priority, then waiting longer to receive the second dose is the better option, Dr Quinn said.

    But in places where there are high levels of community transmission, such as the UK, fast-tracking second doses may be a better option.

    “It makes good sense to try and build people’s immunity up to a decent level quicker, and perhaps accept a slightly lower level of antibody responses,” Dr Quinn said.

    “It’s understanding those trade offs and understanding what’s best for that particular population.”

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