Global Statistics

All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm

Global Statistics

All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
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What Are The Stages Of Covid-19

When To See Your Doctor

Different Stages of Covid -19

Talk with your doctor right away if you think you have COVID-19 or you notice symptoms.

Your doctor will advise you on whether you should:

  • stay home and monitor your symptoms
  • set up a telehealth visit
  • come into the doctors office to be evaluated
  • go to the hospital for more urgent care

Theres currently no cure for an infection caused by the 2019 coronavirus. However, many treatments and vaccines are currently under study.

On October 22, 2020, the approved its first COVID-19 treatment, the medication remdesivir . Its available by prescription to treat COVID-19 in people ages 12 years and older whove been hospitalized. Its administered as an intravenous infusion.

In November 2020, the FDA also granted EUAs to monoclonal antibody medications.

Monoclonal antibodies are synthetically derived proteins that help the body develop an immune response against foreign-made substances such as viruses.

These medications are:

Like remdesivir, theyre also administered by IV infusion and intended to treat COVID-19 in people ages 12 years and older. Monoclonal antibodies can also be given subcutaneously . These medications are used for outpatient therapy.

There was hope for convalescent plasma, which was intended for treatment in people who are hospitalized or at high risk for hospitalization. But the latest studies are showing no benefit and perhaps even harm from it. With the advent of monoclonal antibodies, it isnt given anymore.

Stage Iii: Hyperinflammation Phase

Figure 9. Stage III of a COVID-19 infection, the hyperinflammation phase, in which the infection runs wild and patients often deteriorate suddenly .

These patients often deteriorate suddenly, usually developing ARDS. Acute respiratory distress syndrome involves inflammation and fluid build-up in the lungs, which prevents oxygen transfer from the air to the blood.

Figure 10. Fluid build-up in the alveoli and inflammation prevents oxygen transfer in patients with acute respiratory distress syndrome , a) normal alveoli with efficient gas exchange, b) inflammation of the airway as seen in ARDS, c) inflammation of the airway and fluid build-up in the alveoli as seen in ARDS, d) decreased oxygen transfer due to fluid accumulation and inflammation of the airway.

Blood oxygen levels drop rapidly and the patient struggles harder to breathe. Patients with ARDS usually require mechanical ventilation in the intensive care unit . On average, patients are intubated between 14.5 days after symptom onset. Depending on the country, and the ICU setting, approximately half of ARDS patients will recover, and half will die.

How Long Does Parosmia Last

Parosmia can potentially persist for weeks or months after developing COVID-19.

In a May 2021 study , researchers examined a group of 268 people who developed parosmia after having COVID-19. They found the participants had smell alteration that lasted from about 10 days to 3 months. Every person in the study either had a partial or complete loss of smell before developing parosmia.

More than 75 percent of people also had an altered sense of taste and only 0.7 percent had other nasal symptoms, such as a runny or stuffy nose.

In another study published in March 2021, researchers found that in a group of 195 healthcare workers with COVID-19, 125 developed dysfunction of their ability to smell, and 118 developed taste dysfunction.

The researchers found that 89 percent of the study participants had full or partial recovery within 6 months, and most of them recovered to some degree within the first 2 months.

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What Is The 2019 Coronavirus

In late 2019, a new virus began generating headlines all over the world because of the unprecedented speed of its transmission.

Its origins have been traced to a food market in Wuhan, China, in December 2019. From there, its reached countries as distant as the United States and the Philippines.

The virus has been responsible for over 200 million infections globally, causing over 4.5 million deaths. The United States has had the most deaths.

COVID-19, which stands for coronavirus disease 2019, is the disease caused by contracting SARS-CoV-2.

Lets bust some myths.

Read on to learn:

  • how this coronavirus is transmitted
  • how its similar to and different from other coronaviruses
  • how to prevent transmitting this virus to others if you suspect youve contracted it


Stay informed with our live updates about the current COVID-19 outbreak.

Also, visit our coronavirus hub for more information on how to prepare, advice on prevention and treatment, and expert recommendations.

Doctors and scientists are learning new things about this virus every day. So far, its known that COVID-19 may not cause any symptoms for some people.

You may carry the virus for

  • rash

However, individuals with COVID-19 may have some, all, or none of the above symptoms.

For instance, fever is often referred to as the most common symptom of COVID-19. However, a July 2020 study of 213 people with mild disease found that only 11.6 percent of them had experienced fever.

Preclinical Stage: How Will This Vaccine Work

4 Phases of COVID

This research-intensive stage is designed to find natural or synthetic antigensforeign substances that induce an immune reaction in your bodythat trigger the same reaction an actual virus or bacteria would. Identifying the right antigen or antigens can often take up to four years.

The FDA also monitors adverse events that may occur related to receiving the vaccine, including through its Vaccine Adverse Event Reporting System and Phase 4 clinical trialsoptional studies pharmaceutical companies may be required to perform after a vaccine is licensed to continue to monitor safety and effectiveness.

The end result: A potentially life-saving vaccine for COVID-19 thats been developed in months, which is something that, up until now, has been virtually unheard of, Dr. Redlich says. But there is an urgent medical need for us to do this, and do it safely.

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We’re Tired Of Watching People Die From A Preventable Disease

The delta surge feels different from the surge last winter. Patients get sicker faster. They go from OK to not OK in a matter of hours, and in extreme cases minutes. I had one patient who looked fine in the morning, and by lunchtime I had to put a breathing tube in, and by dinner time, we were doing CPR.

They’re younger, too. The last time I was in the COVID-19 ICU, I don’t think I had one patient over the age of 60.

It’s been said over and over again, but it’s profoundly true. We’re sick of this. Just like everyone else, we don’t like wearing masks all the time or limiting what events we can go to or the people we can see. We’re tired of the pandemic, too. If there’s a huge influx of hospitalizations because of omicron, I don’t know what we’ll do. We have nowhere to put these people. The hospital is full and we’re tired.

We’re tired of seeing our patients struggling to breathe.

We’re tired of people dying from a preventable disease.

We’re tired of watching young folks die alone.

We’re tired of family members being aggressive with care providers because we’re not giving the drugs the internet or the news told them were better. When all those things have not been proven to be helpful whatsoever.

We’re tired of COVID-19, just like everyone else is. But everyone else doesn’t have to watch people suffer and die on a daily basis.

Stage : Pneumonia/respiratory Symptoms

Stage 2 is when the virus moves into your lungs and causes pneumonia. This is the critical stage where you must watch closely for trouble breathing, chest pain and confusion.

“When youre constantly coughing and cant take deep breaths, your oxygen level can decrease,” Sandra said. “If the oxygen saturation in your blood is not at a satisfactory level, you will be admitted, and well start treatment.”

Respiratory therapists work closely with hospitalists and pulmonologists to treat COVID-19 patients. They will try to increase your flow of oxygen first with non-invasive equipment similar to what some people use at home for sleep apnea. You can also perform breathing exercises and receive anti-virals, steroids and other medications deemed appropriate by your doctor.

“Our pulmonologists, Dr. Shivaram and Dr. Adarkwah, do everything they can to keep patients out of the ICU unless medically necessary,” Sandra said.

In addition to pneumonia and other severe respiratory problems, at this stage you might require emergency care for blood clots. If you can’t walk across the room without getting winded, seek emergency care immediately. The Emergency Department physician will order blood work and other tests to determine the proper treatment for your condition.

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Seroconversion Stages Covid19 Into Distinct Pathophysiological States

  • Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, United States
  • Department of Pharmacology, University of Colorado Anschutz Medical Campus, United States
  • Department of Pediatrics, Division of Developmental Biology, University of Colorado Anschutz Medical Campus, United States
  • Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, United States
  • Data Science to Patient Value, University of Colorado Anschutz Medical Campus, United States
  • Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, United States
  • Department of Biostatistics and Informatics, Colorado School of Public Health, United States
  • Department of Emergency Medicine, University of Colorado Anschutz Medical Campus, United States
  • Department of Pediatrics, Sections of Informatics and Data Science and Critical Care Medicine, University of Colorado Anschutz Medical Campus, United States
  • Department of Pediatrics, Division of Allergy/Immunology, University of Colorado Anschutz Medical Campus, United States
  • eLife10

    Extubation Followed By A Long Road Of Therapy

    Experts outline 3 stages of COVID-19 infection

    Hopefully, we can fix you and get you off the ventilator. Like I mentioned earlier, survival after intubation has the same odds of a coin flip. Extubation is a good thing because it means you survived the ventilator, but your battle is far from over.

    Many times intubation requires a medically induced coma, meaning you’re deeply sedated, similar to being under general anesthesia for surgery. Despite deep sedation, some patients still don’t tolerate mechanical ventilation due to excessive coughing, or dysynchrony with the ventilator. Sometimes, we need to chemically paralyze you in order to completely take over function of your body. This allows us to make certain that you are able to achieve optimal support from the ventilator. Some COVID patients require days, if not weeks of sedation and paralysis.

    After a long run on a ventilator, many patients are profoundly weak. This is a consequence of the long term sedation and paralysis that many patients require in order to recover from COVID-19. Like anything else in the body, if you don’t use it, you lose it. Patients lose up to 40% of their muscle mass after being intubated for 20 days. This leads to many issues after extubation that will require weeks of rehabilitation and recovery. In some circumstances, patients are so weak that they require placement of a tracheostomy to allow slow weaning from the ventilator. A tracheostomy is a surgically inserted airway device directly into your windpipe in your neck.

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    Stage 3 Peak Infection And Crisis Management

    Stage 3 states are seeing peak infection rates. Health systems and clinics that treat COVID-19 patients may see their resources depleted and healthcare workers exhausted. Those that do not provide critical care may be temporarily closed or operating virtually. One important thing to note is that stage 3 states will look very different across the country as peak rates of infection are much higher in some areas versus others. For this reason, it may be possible to see states move from stage 1 to 3, with some states never experiencing the need for statewide measures. These states peak infection rates may remain manageable without seeing any major operational disruptions. In Stage 3, some of the most pressing issues include:

    Testing, Screening, and Risk Management for Patient Populations: The testing and population health management needs from previous stages continue to be top priorities in Stage 3.

    Virtual Managed Care and Patient Outcome Checks: Patients will continue to need the ability to access various types of care during the COVID-19 pandemic. Although in-person appointments and care may not always be an option, you can support patients through a combination of virtually managed care and patient check-ins. For example, you can ask patients to self-report health outcomes from home and monitor for issues. By doing this, you can identify problems and intervene or schedule virtual telehealth visits as needed.

    How To Feel Better

    Theres no treatment for COVID-19, although if you have to stay in the hospital, some medicines may shorten your recovery.


    Some of the things you can do to speed your healing are similar to how you might take care of the flu or a bad cold.

    Eat healthy foods. If you feel like eating, fuel your body with the vitamins and nutrients it needs to get better. Limit sugary or highly processed foods like cookies and sodas. If you dont have an appetite, you dont need to try to force food down.

    Drinks lots of fluids. Do this even if you dont feel like eating. Water is always a good pick.

    Lower your fever. Take acetaminophen or ibuprofen if you have a temperature or body aches. Be careful not to take more than a total of 3,000 milligrams every 24 hours. That includes acetaminophen alone as well as in medications like cold and flu pills and syrups.

    Rest. Know that youll probably feel better eventually. If your symptoms do get worse, call your doctor.

    J. Randall Curtis, MD, A. Bruce Montgomery, American Lung Association Endowed Chair in Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle.

    World Health Organization: Coronavirus disease 2019 Situation Report — 41, Report of the WHO-China Joint Mission on Coronavirus Disease 2019 , WHO Director-General’s opening remarks at the media briefing on COVID-19 — 24 February 2020.

    National Health Service : Cough.

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    Broad Range Of Symptoms

    Glatter shared his experience treating patients with COVID-19 in New York City.

    In general, while fever is usually the most commonly described initial symptom of COVID-19 infection, the reality of what I see on the front lines is more variable, he said.

    In fact, some patients may present only with loss of taste or smell and otherwise feel well, Glatter said. I have also seen patients present with COVID-toes, or chilblains. A livedo-type of skin reaction in response to acute inflammation, in the absence of fever, cough or other respiratory symptoms.

    Glatter said that other patients have also presented with malaise, headache, and dizziness, that in some ways resemble the symptoms of stroke, but without fever, cough, or any evidence of upper respiratory symptoms.

    I have also seen patients present only with chest pain, devoid of any respiratory symptoms, he said. The onset of nausea, vomiting, and diarrhea after onset of respiratory symptoms such as fever and cough may also suggest that a person may have COVID-19.

    According to Glatter, the bottom line is that healthcare professionals need to be vigilant and keep an open mind when evaluating patients who may have symptoms associated with the disease. They dont always present according to the book, so you must cast a wide net when thinking about who may or may not have COVID-19, he said.

    Were Tired Of Watching People Die: Unmc Doctor Details 6 Stages Of Critical Covid

    Scientific Review of COVID

    OMAHA, Neb. – Weve shown you the horrific images and weve shared the gut-wrenching stories.

    Still, a University of Nebraska Medical Center doctor says watching coronavirus ruin futures and families doesnt seem to be enough to get people to do their part and help end this pandemic.

    So, he wrote an eye-opening article, outlining not just the beginning or end of a battle with COVID-19, but detailing the often debilitating progression. Its titled Were tired of watching people die: The 6 stages of critical COVID-19 care, written by Dr. Shaun Thompson of UNMC, a critical care anesthesiologist.

    He said that whether it takes days or weeks for the virus to worsen, many patients start similarly.

    Theyll come in, and maybe their oxygen levels may be a little low, he said, listing common virus symptoms like fever, fatigue, and sometimes a cough.

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    Whats The Recovery Time For Coronavirus

    Early research suggested that it could take 2 weeks for your body to get over a mild illness, or up to 6 weeks for severe or critical cases. Newer data show that recovery varies for different people, depending on things like your age and overall health. Fatigue, headache, and trouble breathing were the symptoms most likely to linger.

    CDC guidelines say that if youve been sick, you should isolate yourself at home until all of these things are true:

    • You havent had a fever for 24 hours without using a fever-reducing medicine.
    • Your symptoms are better, though they might not be totally gone.
    • Its been at least 10 days since your symptoms started.

    What Are The Stages And Symptoms Of Covid

    • Day 1: The symptoms usually start with a fever, a dry cough and mild breathing issues which may get worse over the next week. You also may have symptoms of a sore throat, coughing up mucus, diarrhea, nausea, body aches and joint pain.
    • Day 7: Breathing may become difficult or laboured. This is called dyspnoea.
    • Day 9: Sepsis may start, this is the body’s extreme response to an infection that can lead to organ failure or injury.
    • Day 10-12: People who have mild COVID-19 start to have an improvement in their fever and cough, but in serious cases their fever and cough continues.
    • Acute respiratory distress syndrome starts to be diagnosed, this is a respiratory problem when there is widespread inflammation in the lungs.
    • Day 12: This is the median day to be admitted into the intensive care unit .
    • Day 15: Acute kidney and cardiac injury becomes evident.
    • Day 18.5: The median time it takes from the first symptoms of COVID-19 to death is 18.5 days.
    • Day 22: This is the median amount of days it takes for COVID-19 survivors to be released from hospital

    A study published in The Lancet studied the patients who were hospitalized with COVID-19 and compared details of the patients who passed away and patients that survived.

    This figure below shows the progression and duration of the major symptoms of COVID-19 in survivors and non-survivors for hospitalized patients in the study.

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