Study Suggests Blood Type Could Impact Likelihood Of Contracting Covid
A new study suggests that a persons blood type could impact their susceptibility to COVID-19.
Its worth pointing out that the study does not show that people with blood types B and O are immune to the virus, but it does suggest that blood type A individuals are more likely to get infected. Scientists have stressed that the study does not offer a clear indication on how COVID-19 impacts people of different blood types, but it is a step forward for coronavirus research.
It is interesting that the viral RBD only really prefers the type of blood group A antigens that are on respiratory cells, which are presumably how the virus is entering most patients and infecting them,said Sean Stowell, co-author of the study. Blood type is a challenge because it is inherited and not something we can change. But if we can better understand how the virus interacts with blood groups in people, we may be able to find new medicines or methods of prevention.
Blood Advances published a similar study last year that showed people with blood type O were the least likely to get infected by COVID-19.
What Do Experts Make Of This Link Between Blood Type And Covid
While it’s unclear what’s going on with the link between blood type and COVID-19, “there has been ongoing research work to identify the risk factors that increase the risk of COVID infection,” Anupama Nehra, MD, an assistant professor at the Rutgers New Jersey Medical School and clinical director of hematology oncology at Rutgers Cancer Institute at University Hospital, tells Health.
There are some theories on why there might be a link: Your red blood cells are covered with molecules that are known as antigens, Thomas Russo, MD, professor and chief of infectious disease at the University at Buffalo, tells Health. These antigens help prompt a response from your body’s immune system. It could be that antigens for people with type O blood block the spike protein in SARS-CoV-2, the virus that causes COVID-19, and keeps it from entering into your cells, Dr. Russo says. Blood types can also serve as receptors for viruses and bacteria, and that could be another factor, he says. Or, Dr. Russo says, there may be some other, completely different component of type O blood that works to prevent infection.
But again, experts really don’t know what’s behind all of this. “We still do not understand all the factors at play,” Dr. Nehra says.
Other Studies Confirm The Connection
Additionally, a November 2020 study published in the medical journal Nature also found that blood type influences COVID risk. “Recent evidence suggests blood type may affect risk of severe COVID-19,” it explained. This study involved 14,000 individuals in the New York Presbyterian hospital system and found that those with non-O blood types had a “slightly increased” infection prevalence.
“Risk of intubation was decreased among A and increased among AB and B types, compared with type O, while risk of death was increased for type AB and decreased for types A and B,” researchers concluded. “Our results add to the growing body of evidence suggesting blood type may play a role in COVID-19.”
Studies Show Link Between Blood Types From A To O And The Body’s Response To The Coronavirus
En español | In the last several months, a number of studies have drawn a connection between blood type and COVID-19 risk, and most have reached the same conclusion: People with type O blood, the most common kind, may have a slight advantage over their peers when it comes to risk for a coronavirus infection and hospitalization or death from COVID-19. This, however, does not mean they can’t contract the virus or fall seriously ill from it.
Researchers in Denmark found that among more than 7,400 people who tested positive for COVID-19, fewer individuals had type O blood compared to type A, despite the fact that the two blood types accounted for the same share of the population when compared to a larger control group. Canadian researchers reached a similar finding in their retrospective study published in Annals of Internal Medicine. They found that people with type O blood had a lower risk for contracting the coronavirus compared to those with type A, B or AB. They also observed that individuals with type O blood had a slightly lower risk for getting severely ill or dying from COVID-19 if they did become infected. And several other peer-reviewed studies reinforce these findings.
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Even still, experts caution that the accumulating evidence on this subject shouldn’t influence everyday medical or public health decisions.
Should I Have The Astrazeneca Vaccine
Jo Jerrome, chief executive of Thrombosis UK: “The Joint Committee on Vaccines and Immunisation and Expert Haematology Panel have advised that anyone with a history of blood clots are at no increased risk from the AstraZeneca Covid-19 vaccine.”
Public Health Wales: “Public Health Wales supports the expert scientific advice of UK expert groups that the benefits of vaccination with all Covid-19 vaccines in use continue to outweigh the risks of Covid-19.
“Covid-19 has caused over 120,000 deaths in the UK, with an average of 30 deaths a day still being reported. The vaccination programme has already saved over 6,000 lives.”
Fact Check: Coronavirus Does Not Affect People With O+ Blood Type Is Misleading
The post claiming coronavirus does not affect people with O+ blood type is misleading.
A viral post on social media claims that coronavirus does not affect people with O+ blood type. Vishvas News spotted the post first on Facebook. We found it on a page Namma Vadaloor with 2,189 followers. Several posts in Whats app and Helo app have also made the claim. Vishvas news investigation revealed the claim is misleading.
A post on social media claims that coronavirus does not affect people with O+ blood type. An access to the archived post is provided here.
On investigation, we found that the claim has come on the basis of a research article published by an US based company 23andMe in California. The research article mentions that preliminary investigations have lend more evidence for the importance of a persons blood type determined by the ABO gene in differences in the susceptibility to the virus.
The research conducted with over 7,50,000 participants states, The preliminary data suggest that O blood type appears to be protective against the virus when compared to all other blood types. Individuals with O blood type are between 9-18 per cent less likely than individuals with other blood types to have tested positive for Covid-19.
Even among people with high chances of exposure to Covid-19, like healthcare workers, those with O blood types were 13 to 26 per cent less likely to test positive, according to the research.
Healthhow Blood Type May Affect Your Coronavirus Risk
“A higher proportion of Covid-19 patients with blood group A or AB required mechanical ventilation and had a longer ICU stay compared with patients with blood group O or B,” the study authors wrote.
Types A and AB were also more likely to need a type of dialysis that helps the kidneys filter blood without too much pressure on the heart.
There are important caveats to consider from the new research. There is zero indication that any blood type is either totally protective or dooms a patient to severe outcomes of Covid-19.
Public health officials say that people with any blood type need to take the same mitigation precautions, such as wearing a mask and maintaining physical distancing and effective hand-washing. These studies only suggest an association between blood types and Covid-19 outcome, not cause and effect.
Still, a link between blood type and severity of diseases is not unheard of. People with blood type O, for example, tend to become sicker from cholera than people with other blood types. Cholera is a bacterial infection that affects the small intestine.
Silverstein called the new research “interesting cocktail party conversation.”
Maybe with further study, he said, “it could lead to new approaches for prevention or therapy.”
“But at the present time, there is no reason to think that if you have type O blood, you’re protected from Covid-19.”
Unfortunately This Might Be A Covid Risk Factor That Can’t Be Controlled
The study’s authors pointed out that unlike other potentially high-risk conditions, nothing can be done to lessen the risk created by our genetic makeup. “Blood type is a challenge because it is inherited and not something we can change,” Stowell said. “But if we can better understand how the virus interacts with blood groups in people, we may be able to find new medicines or methods of prevention,” he added.
The study authors said the findings also raised even more questions that warranted further examination. “Does this really influence the ability of the virus to get into cells? Does it just influence its ability to adhere to the cells? That’s open-ended,” Stowell said. “We’re working on that right now, but the jury is still out.” And for more on how you can help improve your odds, check out These 3 Vitamins Could Save You From Severe COVID, Study Finds.
Study Finds Possible Link Between Blood Type And Covid
Do you know your blood type? If not, you might want to find out, because a new study has found evidence that certain blood types could be associated with a greater risk of contracting COVID-19.
Researchers at Emory University School of Medicine and Harvard Medical School assessed a protein on the surface of the SARS-CoV-2 virus called the receptor binding domain, or RBD. The RBD is the part of the virus that attaches to the host cells, so it is an important research target for understanding how infection occurs. The study was .
The scientists assessed synthetic blood group antigens on respiratory and red blood cells found in people with blood types A, B, and O, and analyzed how the SARS-CoV-2 RBD interacted with each. They found the RBD had a strong preference for binding to blood group A found on respiratory cells. The RBD showed no preference for group A red blood cells, however, or any of the other respiratory or red cells.
Stowell said the teams findings alone cant fully describe or predict how coronaviruses like SARS-CoV-2 would affect patients of various blood types.
Our observation is not the only mechanism responsible for what we are seeing clinically, but it could explain some of the influence of blood type on COVID-19 infection, he said.
This Blood Type May Protect You Against Covid Study Says
Over the last year, researchers have continued to study risk factors for COVID-19. One of them? Blood type. According to a number of studies there is one blood type in particular that seems to be more protective when it comes to the virus, and people with it, are less prone to severe infection and even death. Read on to learn about the latest major study linking blood type to COVID riskand to ensure your health and the health of others, don’t miss these Signs Your Illness is Actually Coronavirus in Disguise.
Are People With Type A Blood More Likely To Die From Covid
So people with Type A may be more likely to catch the virus, but whether they also get it worse is still unclear: the NEJM study reports that people with Type A blood were also more likely to have respiratory failure.
However, the research out of Columbia University found there wasnt really any difference among intubations or death and different blood types. And a recently released study in the Annals of Hematology looked specifically at the link between blood types and the need for intubation or death in confirmed COVID-19 patients. They found no link between blood type and the severity of the illness. The new research in Blood Advances, mentioned above, had similar findings. Although true to the unending questions aroung this new disease, another, smaller study, also in Blood Advances, suggested that blood types A or AB had higher risk of certain intense interventions and longer ICU stays, but the researchers themselves considered the link to be so far unresolved.
So If Im O Am I Safe From The Coronavirus
Just because youre Type O doesnt mean youre in the clear. All studies so far have only looked at blood type in connection to symptomatic cases of coronavirus, Dr. Aronoff points out.
We dont know about asymptomatic carriersthat is, Type O could still pass along the virus to other people unknowingly just as much as Type A could.
“There are two possibilities: You’re Type O so you might not contract the virus because it has no landing stripthere’s nothing to attach to,” Dr. Udden explains. “Or by being Type O, the virus gets in but the A antibody prevents it from docking with enough cells to cause disease. But the virus is still in your system and you can still pass it to someone else.”
I Am Over 30 And Have A History Of Blood Clots
Jo Jerrome, chief executive of Thrombosis UK: “All current scientific bodies studying and monitoring reported blood clots following the AstraZeneca vaccine have advised that anyone with a history of blood clots are at no increased risk from the AstraZeneca Covid-19 vaccine.”
Public Health Wales: “The expert scientific advice from the JCVI is that risk benefit remains strongly in favour of vaccination with the AstraZeneca vaccine for those aged 30 and over, and those aged under 30 who have underlying health conditions which puts them at higher risk of severe outcomes from Covid-19 infection.”
Is The Vaccine Safe
Dr. William Schaffner, an infectious disease expert at Vanderbilt University in Tennessee, said both the Moderna and Pfizer vaccines are safe.
Scientifically, these vaccines have been rigorously examined by now two external, tough committees, people not associated with the companies or the government, Schaffner told Healthline. And they have passed both committees with flying colors.
Dr. Anne Liu, an infectious disease physician at Stanford Health Care in California, said theres no reason to worry about any potential long-term side effects from the vaccination.
People who are worried about long-term side effects may somewhat misunderstand how vaccines work. This is not something that stays in your body very long, and the immune response that is generated is fairly quick and should settle down fairly quickly over several weeks, Liu told Healthline.
Its not like medications that can accumulate in your body. Its not something that changes anything about your makeup so you can have effects from it later on, she said.
Experts said theres no real difference in terms of safety or efficacy between the Moderna and Pfizer vaccines.
To my assessment, they look very similar both in terms of safety and in terms of effectiveness, so Im not recommending any preference for one over another, Dr. Dean Blumberg, chief of pediatric infectious diseases at the University of California Davis, told Healthline.
For the large majority of people, the COVID-19 vaccine is safe.
The Coronavirus Is More Likely To Attach To A Specific Kind Of Type A Blood Cell
The team of scientists at Harvard and Emory conducted a laboratory study to better understand how SARS-CoV-2 interacts with A, B, and O blood types. The researchers focused on the part of the virus known as the receptor binding domain , which the pathogen uses to attach to cells once it enters the body.
The results, which were published in the journal Blood Advances, showed that the virus was more likely to attach to type A cells, specifically the type of blood cells found lining the respiratory system. The virus showed no preference for cells from other blood types or respiratory cells from the B or O blood groups, as Live Science reports.
The study authors believe that their results can help explain why some people are more susceptible to COVID. “It is interesting that the viral RBD only really prefers the type of blood group A antigens that are on respiratory cells, which are presumably how the virus is entering most patients and infecting them,” Sean Stowell, MD, one of the study’s authors from Brigham and Women’s Hospital in Boston, said in a statement.
Blood Types And Diseases
Experts say research shows many diseases have been linked to blood types.
We found that type AB is related to stroke risk and in general, to cognitive impairment risk. Although not all studies have observed that, Cushman said.
Type O, compared to other types, also protects against heart attacks and blood clots in the veins, known as venous thrombosis, she added.
We dont know the mechanisms yet, but we know there are differences by blood type in certain clotting factors and factors in the circulation that relate to blood vessel lining cell connections, Cushman said.
Norovirus has a clear biological reason why blood type would make a difference, she said. The norovirus actually uses the sugars on the cell surface to attach itself to the cell.
In general, people who dont make the H1-antigen and those with B type blood will tend to be resistant, whereas people with A, AB, or O blood types will tend to get sick.
Why The Information Can Be Misunderstood
The NIH reports people have questioned why most get mild cases of the virus while others fall into severe respiratory distress and even death after getting sick.
Officials with the NIH also say there have been cases of young people, who are otherwise healthy, getting COVID-19 and becoming very ill. So why is that the case?
According to the National Institute of Allergy and Infectious Diseases, virus severity is most often linked with genes.
The two stretches of DNA implicated as harboring risks for severe COVID-19 are known to carry some intriguing genes, including one that determines blood type and others that play various roles in the immune system, the institute found.
Study Finds No Relationship Between Blood Type And Severity Of Covid
This article is part of Harvard Medical Schools continuing coverage of medicine, biomedical research, medical education and policy related to the SARS-CoV-2 pandemic and the disease COVID-19.
Blood type is not associated with a severe worsening of symptoms in people who have tested positive for COVID-19, report Harvard Medical School researchers based at Massachusetts General Hospital.
Their findings, published in the Annals of Hematology, dispel previous reports that suggested a correlation between certain blood types and COVID-19.
The study did find, however, that symptomatic individuals with blood types B and AB who were Rh positive were more likely to test positive for COVID-19, while those with blood type O were less likely to test positive.
We showed through a multi-institutional study that there is no reason to believe being a certain ABO blood type will lead to increased disease severity, which we defined as requiring intubation or leading to death, said senior study author Anahita Dua, HMS assistant professor of surgery at Mass General.
This evidence should help put to rest previous reports of a possible association between blood type A and a higher risk for COVID-19 infection and mortality, Dua said.
I Had A Blood Clot A Few Years Ago
Jo Jerrome, chief executive of Thrombosis UK: “All evidence and current guidance advises that people with a history of blood clots are at no increased risk and the benefits for most, especially those above the age of 30, of having a Covid vaccination outweigh the risk of this very rare syndrome.
“However, if an individual has concerns or is uncertain, they should speak to their GP.”
Public Health Wales: “Public Health Wales advises that anyone with a history of a blood clot should speak to their GP ahead of their vaccination.”
Blood Type Doesn’t Affect Your Covid Risk
MONDAY, April 5, 2021 — A or B, AB or O, it doesn’t matter — your blood type has nothing to do with your risk of contracting severe COVID-19, a new study concludes.
Early in the pandemic, some reports suggested people with A-type blood were more susceptible to COVID, while those with O-type blood were less so.
But a review of nearly 108,000 patients in a three-state health network has found no link at all between blood type and COVID risk.
“Since the beginning of this pandemic, there have been associations postulated between blood type and disease susceptibility,” said Dr. Amesh Adalja, a senior scholar with the Johns Hopkins Center for Health Security.
“From this large study, it appears that there is no association between blood type and susceptibility or severity, and other explanations were likely present,” added Adalja, who had no role in the study.
An early report from China suggested that blood type might influence COVID risk. Subsequent studies from Italy and Spain backed that up, researchers said in background notes.
However, other studies out of Denmark and the United States offered mixed and conflicting results.
To clear things up, researchers led by Dr. Jeffrey Anderson, from Intermountain Medical Center Heart Institute in Murray, Utah, analyzed data from tens of thousands of patients with Intermountain Healthcare, a nonprofit health system of 24 hospitals and 215 clinics in Utah, Idaho and Nevada.
‘everybody Needs To Be More Careful Regardless Of Blood Type
Despite the growing body of research suggesting some link between COVID-19 and blood type, experts say these studies don’t change much for the individual. It’s unlikely that doctors will make treatment decisions based on blood type, Silverstein says, and he cautions that blood type should not be considered on the same level of risk as age, obesity or other underlying health conditions.
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A June report from the Centers for Disease Control and Prevention found that hospitalizations for people with COVID-19 were six times as high for patients with chronic health conditions like heart disease, lung disease and diabetes, compared to otherwise healthy individuals. Deaths among this population were 12 times as high. What’s more, 95 percent of COVID-19 deaths in the U.S. have occurred in adults 50 and older.
“If you’re type A blood, you might be at a slightly higher risk than if you’re type O. But that doesn’t mean you should be more careful; everybody needs to be more careful. And that the worst thing that can happen is that people let their guard down, Silverstein says.
Other Facts May Complicate Your Chances Of Infection
“Blood type is not the only factor in disease severity,” says Nebraska Medicine. “How much virus you were exposed to, your age, plus any of your underlying health conditions also affects the course and severity of the disease. Say, for example, you and your friend who have the same susceptibility are both sharing a bus with someone who has asymptomatic COVID-19. Your friend sits next to the person infected. You sit 7 feet away from both of them. Your friend would have a worse case of COVID-19 because they were infected with more virus.”
What The March Study Reported
The March study came out of Wuhan, China, where the first known cases of COVID-19 were discovered.
In the study, scientists looked at the blood types of 2,173 people who had been diagnosed with COVID-19 and compared that with the blood types of the general population in that region.
They found that in the normal population, type A was 31 percent, type B was 24 percent, type AB was 9 percent, and type O was 34 percent.
In those with the virus, type A was 38 percent, type B was 26 percent, type AB was 10 percent, and type O was 25 percent.
The researchers concluded that blood group A had a significantly higher risk for COVID-19 compared with non-A blood groups. Whereas blood group O had a significantly lower risk for the infectious disease compared with non-A blood groups.
Experts expressed concerns after the recent study that people with blood types other than type A might let their guard down.
Similar sentiments were expressed after the March study.
This is an interesting study, said Patricia Foster, PhD, a microbiologist and professor emerita of biology at Indiana University, told Healthline in March. But it needs verification. If they can come up with more solid numbers and bigger studies, its something to look out for.
Its very compelling and the results are not entirely surprising since we know blood group is important in other settings and other viruses, she added.