Global Statistics

All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm

Global Statistics

All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
All countries
Updated on June 23, 2022 8:27 pm
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What Is Best Covid Vaccine

Securing Safe And Effective Vaccines

Which COVID-19 vaccine is the best? | DW News

The European Commission has been negotiating intensely to build a diversified portfolio of vaccines for EU citizens at fair prices. Contracts have been concluded with 8 promising vaccine developers, securing a portfolio of up to 4.2 billion doses.

Deliveries of vaccine doses to European Union countries have increased steadily since December 2020. Vaccination has gathered pace across the European Union.

Effective and broad vaccination is the best strategy to overcome the pandemic. Based on current evidence, all vaccines authorised in the EU are highly protective against hospitalisation, severe disease and death, with an effectiveness in the general population of over 80%.

There is a clear link between the level of vaccination and hospitalisation and death rates: the higher the vaccination rate, the lower the risk of being hospitalised or dying.

Increasing vaccination rates of all eligible groups, particularly of the elderly, the vulnerable and healthcare workers across the EU, therefore remains the first priority to control the spread of COVID-19.

Evidence shows booster doses offer a significant increase in protection against infection and severe diseases. The ECDC therefore recommends a booster for adults, prioritising those over 40, at least 6 months after primary vaccination.

At the same time, the Commission has started work to anticipate and tackle new variants of the virus and to rapidly develop and produce vaccines effective against those variants on a large-scale.

Booster Doses For Healthcare Workers

Healthcare workers on the frontline of the COVID-19 response are at higher risk of infection. The Australian Technical Advisory Group on Immunisation recommends people working in a healthcare settings consider receiving a booster dose. Healthcare workers were prioritised early in the vaccination rollout, so many are due for their booster dose.

Both Vaccines Highly Effective Recommended

The researchers noted that the matched population during the period of Delta dominance was, on average, younger. This group also had a higher percentage of Black participants, current smokers, and those who had received no flu vaccinations in the previous 5 years at a VA facility and it included a lower percentage of those with underlying chronic conditions.

“The 24-week risk of COVID-19 outcomes was low after vaccination with mRNA-1273 or BNT162b2 , although risks were lower with mRNA-1273 than with BNT162b2,” the study authors wrote. “This pattern was consistent across periods marked by alpha- and delta-variant predominance.”

The researchers noted that although early clinical trials and then real-world observational studies found that the Pfizer and Moderna vaccines were both highly effective against symptomatic COVID-19 , no direct comparisons had been attempted.

In the VA news release, first author Barbra Dickerman, PhD, MSc, of Harvard said that both vaccines are recommended because they both are highly effective. However, while the estimated differences in effectiveness were small on an absolute scale, they may be meaningful when considering the large population scale at which these vaccines are deployed,” she said. “This information may be helpful for larger decision-making bodies.”

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Things To Consider Before Buying A Best Covid Vaccine So Far

There are many benefits to purchasing a Best Covid Vaccine So Far. Buying the right product is not an easy task you have to check many things to select the best one in the market. After all, here we are including an in-depth buying guide that will refine your purchasing decision.

Suppose youre new to ratings and reviews or have plenty of experience selecting a product, searching for a new product that can seem like an overwhelming experience. This is true when you dont know what factor to consider before buying a product.

What Has The J& j Booster Data Shown

COVID vaccine: First milestone vaccine offers 90% ...

For an FDA panel meeting in October to discuss authorization of its booster, J& J provided post-booster data from a large global study. The company reported that, in addition to providing 94% protection against moderate-to-severe COVID-19 in the U.S. , a booster shot given two months after the initial dose increased antibody levels by four to six times, compared to one dose alone.

Another report, a real-world study from the CDC conducted from March through August, showed the J& J single shot to be only 71% effective against hospitalization from COVID-19 in U.S. adults without immunocompromising conditions, compared to 93% for Moderna and 88% for Pfizer. But with the booster dose, the J& J vaccine could be equivalent to the mRNA vaccines, Leslie Sude, MD, a Yale Medicine pediatrician who has helped provide vaccinations, said at the time. Some vaccine experts feel that the J& J vaccine should have always been a two-dose series, but have only recently reached the phase of vaccine efficacy monitoring to confirm that idea.

As far as Omicron, the data is still coming in. Most recently, in late December, a study showed that the Johnson & Johnson shot, China’s Sinopharm vaccine, and Russia’s Sputnik V showed no neutralizing activity against Omicron. The study has not yet been peer-reviewed.

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What Are The Side Effects For Each Vaccine

According to Pfizer, about 3.8% of their clinical trial participants experienced fatigue as a side effect and 2% got a headache. The side effects remain similar among young adults and adolescents.

Younger teens receive the same vaccine dosage as adults and have reported the same side effects, mostly sore arms and flu-like fever, chills or aches that signal a revved-up immune system, particularly after the second dose.

Moderna says 9.7% of their participants felt fatigued and 4.5% got a headache.

Like Pfizer and Moderna’s COVID-19 vaccines, the main side effects of the J& J shot are pain at the injection site and flu-like fever, fatigue and headache. These side effects usually start within a day or two of getting the vaccine, according to the CDC.

But the Johnson & Johnson vaccine was recently paused by U.S. regulators as they investigated reports of potentially dangerous blood clots known as cerebral venous sinus thrombosis, or CVST, in a small number of recipients.

The CDC and FDA said in April they were investigating unusual clots in six women that occurred 6 to 13 days after vaccination. All six cases were in women between the ages of 18 and 48. At the time, more than 6.8 million doses of the J& J vaccine had been administered in the U.S., the vast majority with no or mild side effects.

Ten days later, the agencies recommended resuming use of the vaccine, stating the benefits of the inoculations outweighed their risks.

  • Pain

Covid Booster Protection May Wane In About 10 Weeks New Data Shows

Dec. 27, 2021 — Booster shot protection against symptomatic COVID-19 caused by the Omicron variant appears to fade in about 10 weeks, according to new data from Britain.

U.K. health officials shared the data just before Christmas and noted that there havenât been enough severe cases of the Omicron variant to calculate how well boosters protect against severe disease. But they believe the extra shots provide significant protection against hospitalization and death.

âIt will be a few weeks before effectiveness against severe disease with Omicron can be estimated,â U.K. Health Security Agency officials wrote in the report. âHowever, based on experience with previous variants, this is likely to be substantially higher than the estimates against symptomatic disease.â

Since countries began reporting Omicron cases in November, multiple studies have suggested the variant is better at escaping antibodies from vaccination and previous infection, according to The New York Times. The U.K. report adds to that, noting that both the initial vaccine series and booster doses were less effective and faded faster against the Omicron variant than the Delta variant.

Among those who received two doses of the AstraZeneca vaccine, a booster of the Pfizer or Moderna vaccine was 60% effective at preventing symptomatic disease 2 to 4 weeks after the shot. But after 10 weeks, the Pfizer booster was 35% effective, and the Moderna booster was 45% effective.

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How To Get Your Covid

If you’re aged 16 or over you can:

If you cannot book appointments online, you can call 119 free of charge. You can speak to a translator if you need to.

If you have difficulties communicating or hearing, or are a British Sign Language user, you can use textphone 18001 119 or the NHS 119 BSL interpreter service.

Explain Potential Side Effects

Top 8 Vaccines for Covid-19 | Comparison

Trust and open communication are so important, said Dr. Fryhofer. If you don’t tell people what to expect, physicians are going to be sorry because they’re going to get phone calls from patients about side effects.

That is because after getting a COVID-19 vaccine, most people are going to have some sort of side effect, she said. All three vaccines are going to cause a sore arm. You may feel a little bad, maybe a little tired, muscle aches, but it is so much better than getting COVIDand you do have to get that second dose.

You do expect to have more side effects with that second doseonly for Pfizer and Moderna, said Dr. Fryhofer, adding that if day one is the day you get vaccinated … most symptoms are going to be on day two, day three, possibly day four and then they’re usually gone. But for some people, they’re enough to make you not be able to go to work.

Additionally, with the J& J vaccine, its one dose and youre done, so you dont have to go for a second dose, she said. Its just the one time, but for our patients that means youre only going to have side effects one time.

Related Coverage

Learn more from the CDC about myocarditis and pericarditis following mRNA COVID-19 vaccination.

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The Link Between Myocarditis And Covid

Myocarditis, an inflammation of the heart muscle, became a trending topic this spring when the Centers for Disease Control and Prevention reported that it is monitoring a small number of cases of heart inflammation that have arisen in young adults not long after mRNA COVID-19 vaccination. The side effect is considered important but uncommonarising in about 12.6 cases per million second doses administered. And now the Food and Drug Administration has announced it will place a warning on the mRNA vaccines. Its important to note that the vaccination is still recommended for everyone who is eligible.

Vaccine Types For Booster Doses

The Comirnaty and Spikevax vaccines are approved by the Therapeutic Goods Administration and recommended by ATAGI as a COVID-19 booster dose.

You can have the Pfizer or Moderna vaccine as a booster dose regardless of which vaccine you had for your first 2 doses.

You can also receive the Vaxzevria vaccine if you:

  • cant have the Pfizer vaccine for medical reasons
  • had 2 doses of the AstraZeneca vaccine previously.

Read ATAGIs advice on the type of vaccine recommended for booster doses.

  • 1AstraZeneca can be given as a booster dose in some circumstances, see ATAGI’s advice.

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Number Of Doses/amounts Of Vaccine Per Dose

The primary series of both the Moderna and the Pfizer vaccines is two shots: a priming dose, followed by a booster shot. The interval between Moderna doses is 28 days for the Pfizer vaccine, its 21 days.

Each dose of Pfizers contains 30 micrograms of vaccine. Moderna went with a much larger dose of vaccine, 100 micrograms. It means the company is using a little more than three times as much vaccine per person as Pfizer is. While Modernas initial results didnt seem to justify the much larger dose, data suggest the protection the companys vaccine generates is declining at a slower rate than Pfizers is some experts believe the higher dose may be at least partially responsible.

The J& J vaccine is, as mentioned, a single-dose vaccine. The company has also tested a two-dose regimen, with the two shots given 57 days apart. The results from that 30,000-person trial were presented during an Oct. 15 meeting of FDAs Vaccines and Related Biological Products Advisory Committee, as part of its application for an EUA for its booster dose.

The Pfizer And Moderna Vaccines In People With Hiv

Pfizer Covid vaccine 94% effective, study of 1.2m people ...

Registration studies of the Pfizer and Moderna mRNA vaccines in use in Europe and North America did not report on vaccine safety and effectiveness in the small numbers of people with HIV who took part in those trials, but subsequent studies have reported on responses to vaccination in larger groups of people with HIV.

Israeli clinicians have reported results in 143 people living with HIV who received the Pfizer vaccine. All were taking HIV treatment, 95% had an undetectable viral load and the average CD4 cell count was 700. Two doses of the vaccine were able to trigger the production of antibodies in 98% of participants, including in the small number of people with CD4 cell counts below 350. Side effects were generally mild.

An Italian study compared responses to the Pfizer and Moderna vaccines after the first and second dose in 166 people with HIV and a control group of HIV-negative healthcare workers. The study showed that people with CD4 counts above 500 had strong antibody responses to vaccination and these responses were just as strong as those of HIV-negative healthcare workers. People with CD4 counts between 200 and 500 had somewhat weaker responses and people with CD4 counts below 200 had much weaker antibody and T-cell responses.


How well something works . See also ‘efficacy’.

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Vials: Of: Moderna: And: Pfizer: Vaccinejpg

In the first head-to-head comparison of the Pfizer/BioNTech and Moderna mRNA COVID-19 vaccines, Moderna edged out its competition with a 21% lower risk of infection and a 41% lower risk of hospitalization over 24 weeks, according to a study yesterday in the New England Journal of Medicine .

A team led by researchers from Harvard University and the US Department of Veterans Affairs analyzed the electronic medical records of veterans nationwide, almost all of whom received two doses of either the Pfizer or Moderna COVID-19 vaccine from Jan 4 to May 14, 2021. The study period was dominated by the SARS-CoV-2 Alpha variant.

“Both vaccines are incredibly effective, with only rare breakthrough cases,” said study coauthor Juan Casas, MD, PhD, an epidemiologist at Brigham and Women’s Hospital in Boston and a Harvard associate professor, in a VA news release. “But regardless of the predominant strainAlpha earlier and then Delta laterModerna was shown to be slightly more effective.”

In A Sea Of Skeptics This Physician Was One Of Fibromyalgia Patients Few True Allies Or Was He

All three vaccines continue to offer solid protection against severe illness, though there is concern within the Biden administration that this too will weaken if boosters are not given.

A key question at this point is whether the booster shots will solidify protection in a way that is more sustained, or if these additional doses mark the start of a regular booster shot effort.

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How Long Does The Pfizer Vaccine Last What About Moderna

Pfizer and BioNTech said previously that data from their Phase 3 trial showed high levels of protection against COVID six months after second doses.

Research has also suggested the protection the Moderna vaccine gives against COVID-19 lasts for at least six months.

Both reports were based on follow-up tests in dozens of people who received the shots during studies that led to the vaccines use. Those studies were done before troubling new variants, or versions of the coronavirus, had emerged and started to spread.

What About The Safety Of Covid

WATCH: Which COVID vaccine is most effective?

The FDA and other reviewers closely consider diverse populations and include them in the trials. The clinical trials for the first two COVID-19 vaccines included members of underrepresented minorities and older age groups, and people with conditions such as obesity, diabetes, and heart and respiratory conditions.

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Dr Fauci Says He Would Take The J & J Vaccine

“I would definitely take the Johnson and Johnson vaccine,” Dr. Fauci said in a PSA. “This is a vaccine that works and it only requires one dose. The Johnson and Johnson vaccine uses a particular what we call a vaccine platform and you inject it into the body. The body sees that protein makes a good immune response against the entire virus. The COVID vaccine doesn’t give you COVID. The vaccine is just one protein from the virus that induces your body to make a good response against the whole virus. Well, it’s not tested in the United States. It’s 72% effective in preventing you from getting moderate to severe disease, but virtually a hundred percent protective against hospitalizations and death as proven by this trial.”

Do I Still Need To Take Precautions If I Get The Covid

The COVID-19 vaccines are still being studied, as there are things we dont yet know about them. For example, researchers are still trying to determine how long the COVID-19 vaccines will help protect against the virus. And while the vaccines can clearly lower the risk of getting serious disease from COVID, its not yet clear how well they can prevent the spread of the virus to others.

For people who are fully vaccinated , the CDC has guidance on things you can now do , as well as what types of precautions you should still be taking. This guidance is being updated regularly, so check the CDC website for details. The CDC guidance may not apply if you have a weakened immune system , so its important to talk with your health care provider about which precautions you still need to take.

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