Global Statistics

All countries
546,626,378
Confirmed
Updated on June 23, 2022 2:34 am
All countries
519,064,383
Recovered
Updated on June 23, 2022 2:34 am
All countries
6,345,658
Deaths
Updated on June 23, 2022 2:34 am

Global Statistics

All countries
546,626,378
Confirmed
Updated on June 23, 2022 2:34 am
All countries
519,064,383
Recovered
Updated on June 23, 2022 2:34 am
All countries
6,345,658
Deaths
Updated on June 23, 2022 2:34 am
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What Is Janssen Covid Vaccine

Dna Inside An Adenovirus

Comparing Johnson & Johnson Janssen Covid-19 Vaccine to Pfizer and Moderna

The researchers added the gene for the coronavirus spike protein to another virus called Adenovirus 26. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Johnson & Johnson team used a modified adenovirus that can enter cells but cant replicate inside them or cause illness.

DNA inside

DNA inside

an adenovirus

Johnson & Johnsons vaccine comes out of decades of research on adenovirus-based vaccines. In July, the first one was approved for general use a vaccine for Ebola, also made by Johnson & Johnson. The company is also running trials on adenovirus-based vaccines for other diseases, including H.I.V. and Zika. Some other coronavirus vaccines are also based on adenoviruses, such as the one developed by the University of Oxford and AstraZeneca using a chimpanzee adenovirus.

Adenovirus-based vaccines for Covid-19 are more rugged than mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenoviruss tough protein coat helps protect the genetic material inside. As a result, the Johnson & Johnson vaccine can be refrigerated for up to three months at 3646°F .

Expect The Same Side Effects

Aside from the extremely rare blood clots discussed above, the side effects for the J& J vaccine are very similar to those for the mRNA vaccines, including injection-site pain, headache, fatigue, fever, chills and muscle aches, said Dr. Fryhofer.

With most of the side effects occurring within one to two days following vaccination, Dr. Fryhofer recommends choosing a day or two when you dont have a lot of important stuff going on, because you might not feel well.

Dont Compare The Three Vaccines

Dont get caught up necessarily on the numbers game, because its a safe and effective vaccine and what we need is to have as many effective vaccines as possible, said Dr. Irons. Rather than focusing on efficacy rates, accept the fact that now you have three highly effective vaccines.

These vaccines have not been tested head to head, so its impossible to do a really accurate comparison, she said. What matters most is they are all effective at preventing the most severe COVID outcomes, including hospitalization and death.

All three vaccines far exceeded FDAs 50% efficacy threshold, said Dr. Fryhofer.

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How Do The Covid

mRNA Vaccine

Both the Pfizer-BioNTech and the Moderna COVID-19 vaccines are mRNA vaccines. This means they use mRNA to teach the bodys cells how to make a protein which will cause your body to have an immune response and make antibodies. These antibodies then help fight an infection if the virus, which causes COVID-19, later enters the body. These vaccines do not use a live virus they cannot give you COVID-19. Learn more

Viral Vector-Based Vaccines

The Oxford-AstraZeneca and Janssen vaccines are viral vector-based vaccines. This means they use a harmless virus that doesnt cause COVID-19 to act as a vector. When introduced to the body through the vaccine, this vector virus produces a protein that causes your body to have an immune response and make antibodies. These antibodies then help fight an infection if the virus, which causes COVID-19, later enters the body.

Who Should Not Get The Covid

Philippines gives green light to trials of Janssen

You should not get the vaccine if you:

  • have ever had a severe allergic reaction to a previous dose of the COVID-19 vaccine or any of its components or container
  • are younger than the approved age for the vaccine

You should delay getting the vaccine if you:

  • have received another vaccine, besides a COVID-19 vaccine, in the past 14 days
  • have symptoms of an acute or co-existing illness
  • have symptoms of COVID-19
  • have been advised to self-isolate due to a suspected or confirmed COVID-19 infection or close contact with someone who has COVID-19 delay until your period of self-isolation is over

For more information, please read COVID-19 Vaccine Information Sheet.

There are certain situations when you will need to talk to your primary healthcare provider before receiving the vaccine. These include if you:

  • are pregnant, think you may be pregnant or plan to become pregnant
  • have a history of anaphylaxis or immediate allergic reaction to any other vaccine or injectable therapy
  • are receiving immunosuppressing therapies such as stem cell therapy, chemotherapy, CAR-T therapy, immune checkpoint inhibitors, monoclonal antibodies and other targeted agents . You must speak with your treating provider to ensure the timing of vaccine doses and therapies, and you must state that you have spoken to them prior to receiving the COVID-19 vaccine)

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What Covid Vaccines Are Used In Different Countries Including The Uk Us China And Israel

The race to COVID vaccinate is a marathon, not a sprint, with countries around the world looking to multiple suppliers to help get them over the finish line.

With studies showing it’s 95 per cent effective at preventing symptomatic COVID, the Pfizer/BioNTech vaccine has been highly sought after, despite the difficulty in transporting and storing it at below-freezing temperatures.

The Oxford/AstraZeneca vaccine had been rolled out across dozens of countries, but its use was now being limited in some areas after it was linked to a rare side effect causing deadly blood clots.

Both Pfizer and AstraZeneca are approved for use in Australia, with the federal government recommending AstraZeneca be limited to people over the age of 50.

Other coronavirus vaccines in use around the world include the US-manufactured Moderna, China’s Sinovac, also known as CoronaVac, and Sinopharm, Russia’s Sputnik V and the Johnson & Johnson’s Janssen.

Here’s a list of what some countries are using.

  • Pfizer Rollout started December 2020
  • Moderna Rollout started January 2021
  • AstraZeneca Rollout started February 2021

Q: Is It Possible To Make Comparisons About The Effectiveness Among The Three Covid

A: No. The only way to accurately compare the effectiveness of medical products, such as vaccines or drugs, is by direct comparison in head-to-head clinical trials, which did not occur for these vaccines. Furthermore, the clinical trials for these vaccines occurred in different geographic regions and at different points in time with varying incidence of COVID-19. All of the COVID-19 vaccines that the FDA has authorized for emergency use are at least 50% more effective than placebo in preventing COVID-19, consistent with FDA recommendations provided in our October 2020 guidance document, Emergency Use Authorization for Vaccines to Prevent COVID-19. A vaccine with at least 50% efficacy would have a significant impact on disease, both at the individual and societal level.

A: Yes. Overall, 45.3% of participants in the clinical trials identify as Hispanic/Latino, 19.4% Black or African American, 9.5% American Indian or Alaska Native, 3.3% Asian, 0.2% Native Hawaiian or other Pacific Islander, and 5.6% Multiracial.

The demographic characteristics were similar among participants who received Janssen COVID-19 Vaccine and those who received placebo.

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Can I Be Charged An Administration Fee For Receiving The Covid

No. At this time, the provider cannot charge you for a vaccine dose and you cannot be charged an out-of-pocket vaccine administration fee or any other fee if only receiving a COVID-19 vaccination. However, vaccination providers may seek appropriate reimbursement from a program or plan that covers COVID-19 vaccine administration fees for the vaccine recipient .

Q: Since April 13 2021 Have Additional Cases Of Blood Clots With Low Platelets Been Reported To Vaers

COVID-19 Partner Update: Johnson Johnsons Janssen Vaccine EUA

A: Yes. Specifically, as of April 21, 2021, 15 cases of thrombosis with thrombocytopenia following Janssen COVID-19 Vaccine have now been confirmed, involving cerebral venous sinuses and other sites in the body and these have been associated with three deaths. These numbers will likely change over time as additional cases are reported and investigated.

We are informing the public of these cases and note that a causal relationship with Janssen COVID-19 Vaccine is plausible for thrombosis with thrombocytopenia syndrome and we are continuing to monitor the safety of the vaccine and investigating all reports. Specific risk factors for thrombosis with thrombocytopenia syndrome following the Janssen COVID-19 Vaccine and the level of potential excess risk due to vaccination are under investigation.

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What Should I Do About Side Effects

  • If you experience a severe allergic reaction, call 9-1-1 or go to the nearest hospital.
  • Report vaccine side effects to FDA/CDC Vaccine Adverse Event Reporting System . The VAERS toll-free number is , or report online to . Please include “Janssen COVID-19 Vaccine EUA” in the first line of box #18 of the report form.
  • In addition, you can report side effects to Janssen Biotech, Inc. at or .
  • You may also be given an option to enroll in v-safe. V-safe is a new voluntary smartphone-based tool that uses text messaging and web surveys to check in with people who have been vaccinated to identify potential side effects after COVID-19 vaccination. V-safe asks questions that help CDC monitor the safety of COVID-19 vaccines. V-safe also provides live telephone follow-up by CDC if participants report a significant health impact following COVID-19 vaccination. For more information on how to sign up, visit: .

Schedule : Pharmacist Only Medicine

Schedule 3 drugs and poisons, otherwise known as Pharmacist Only Medicines, are substances and preparations for therapeutic use that

  • are substantially safe in use but require professional advice or counselling by a pharmacist
  • require pharmacist advice, management, or monitoring
  • are for ailments or symptoms that
  • can be identified by the consumer and verified by a pharmacist
  • don’t require medical diagnosis, or only require initial medical diagnosis, and don’t require close medical management.

Some states have subsets of Schedule 3 with additional requirements . Only some Schedule 3 medicines may be advertised to the public.

Examples:

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    Q: What Information Is Available About Allergic Reactions

    A: In the study that evaluated safety in 43,783 participants , hives was reported in five vaccine recipients and 1 placebo recipient in the 7 days following vaccination. In this study, there has been one report of severe hypersensitivity reaction, not classified as anaphylaxis, beginning two days following vaccination with Janssen COVID-19 Vaccine. The event was serious and likely related to vaccination.

    In another ongoing clinical study in South Africa, one case of anaphylaxis has been reported following administration of the vaccine.

    The Fact Sheet for Healthcare Providers Administering Vaccine and the Prescribing Information include the following information, and the same general information is also included in the COVID-19 Vaccine Fact Sheets for Healthcare Providers Administering Vaccine and the Prescribing Information for the other authorized COVID-19 vaccines:

    CONTRAINDICATIONDo not administer the Janssen COVID-19 Vaccine to individuals with a known history of a severe allergic reaction to a previous dose of the Janssen COVID-19 Vaccine or any component of the Janssen COVID-19 Vaccine .

    WARNINGSAppropriate medical treatment to manage immediate allergic reactions must be immediately available in the event an acute anaphylactic reaction occurs following administration of the Janssen COVID-19 Vaccine.

    This information is also consistent with the Prescribing Information for all vaccines intended to prevent infectious diseases.

    How Well The Vaccine Works

    Which COVID
    • The J& J/Janssen COVID-19 Vaccine was 66.3% effective in clinical trials at preventing laboratory-confirmed COVID-19 infection in people who received the vaccine and had no evidence of being previously infected. People had the most protection 2 weeks after getting vaccinated.
    • In the clinical trials, the vaccine had high efficacy at preventing hospitalization and death in people who did get sick. No one who got COVID-19 at least 4 weeks after receiving the J& J/Janssen COVID-19 Vaccine had to be hospitalized.
    • CDC will continue to provide updates as we learn more about how well the J& J/Janssen COVID-19 Vaccine works in real-world conditions.

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    Vaccine Pause Showed Systems Strength

    The CDC and FDA acted quickly and issued a joint statement recommending the pause, Dr. Fryhofer said during a recent AMA COVID-19 Update episode about the J& J Janssen COVID-19 vaccine pause. The CDC also released additional information through its Health Alert Network, which could lead to more cases being reported as a result of increased awareness.

    Additionally, the CDC warned that in these cases, heparin, a standard therapy for blood clots, could cause tremendous harm, Dr. Fryhofer added, noting that the CDC advises checking for platelet activating antibodies by doing a platelet factor four antibody test.

    The CDC advises against heparin therapy if platelet factor four antibody test is positive, she said. If PL4 test is positive, use of non-heparin anticoagulants and high dose intravenous immune globulin should be considered. Hematology consultation is also advised.

    After a thorough review, ACIP lifted the J& J Janssen vaccine pause April 23.

    Related Coverage

    AMA President Susan R. Bailey, MD, commended ACIP for reaffirming its recommendation on the use of the Janssen COVID-19 vaccine for those 18 or older under the FDAs emergency use authorization. The population-level data presented during ACIPs meeting clearly demonstrates that the benefits of this approach outweigh the risks, she said.

    Severe Acute Respiratory Syndrome Coronavirus 2

    Severe acute respiratory syndrome coronavirus 2
    Colourised of SARS-CoV-2 with visible
    Atomic model of the external structure of the SARS-CoV-2 virion. Each “ball” is an .

    Severe acute respiratory syndrome coronavirus 2 , also known as the coronavirus, is the that causes , the responsible for the ongoing . The virus was previously referred to by its , 2019 novel coronavirus , and has also been called human coronavirus 2019 . First identified in the city of , , China, the declared the outbreak a on 30 January 2020, and a on 11 March 2020. SARSCoV2 is a that is in humans. As described by the US , it is the successor to , the virus that caused the .

    SARSCoV2 is a virus of the species . It is believed to have origins and has close to bat coronaviruses, suggesting it emerged from a . as to whether SARSCoV2 came directly from bats or indirectly through any intermediate hosts. The virus shows little , indicating that the introducing SARSCoV2 to humans is likely to have occurred in late 2019.

    studies estimate that each infection results in an average of 2.4 to 3.4 new ones when no members of the community are and no are taken. The virus primarily spreads between people through close contact and via aerosols and that are exhaled when talking, breathing, or otherwise exhaling, as well as those produced from coughs or sneezes. It mainly human cells by binding to , a membrane protein that regulates the renin-angiotensin system.

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    Schedule : Prescription Only Medicine

    Schedule 4 drugs and poisons, otherwise known as , are substances and preparations for therapeutic use that

    • require professional medical, dental, or veterinary management or monitoring
    • are for ailments or symptoms that require professional medical, dental, or veterinary diagnosis or management
    • may require further evaluation for safety or efficacy
    • are new therapeutic substances.

    The price of many Schedule 4 substances are subsidized by the through the , when prescribed by an authorized prescriber. Certain medications may require an authority from the . Situations that may require an authority include where the drug may only have benefit in limited conditions, the true cost of the drug is high, or when there is a risk of dependence. Some states have subsets of Schedule 4 with additional requirements . Schedule 4 medicines cannot be advertised directly to the public.

    Examples:

    You Have Other Vaccine Choices

    What Clinicians Should Know About Johnson & Johnson Janssen COVID-19 Vaccine

    The FDA updated the J& J Janssen vaccine EUA with an additional warning, noting that women under 50 should be made aware of a rare risk of blood clots and low platelets following vaccination, said Dr. Fryhofer. They also need to know there are other COVID vaccines out there that dont pose this small risk.

    That empowers patient choice. It also means vaccination clinics should make clear which vaccine or vaccines are being offered and when, she added.

    With the J& J Janssen vaccine, the benefits of the one-dose regimen far outweigh the risks. But, if people are worried, they can access Pfizer or Moderna COVID-19 vaccines. There have been more than 180 million doses of mRNA vaccines by Pfizer and Moderna administered with no reports of cerebral venous sinus thrombosis with thrombocytopenia.

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    What Is The Countermeasures Injury Compensation Program

    The Countermeasures Injury Compensation Program is a federal program that may help pay for costs of medical care and other specific expenses of certain people who have been seriously injured by certain medicines or vaccines, including this vaccine. Generally, a claim must be submitted to the CICP within one year from the date of receiving the vaccine. To learn more about this program, visit or call .

    How Is Janssen Covid

    Read all vaccine information sheets provided to you.

    You will receive a vaccination card showing the date and type of COVID-19 vaccine you received.

    You will be “fully vaccinated” if it has been at least 2 weeks since you received Janssen COVID-19 Vaccine. You may become infected with COVID-19 if the vaccine has not had enough time to provide protection.

    Even after you are fully vaccinated, keep using infection control methods when you are in public or around others who may not have been vaccinated. This includes social distancing, hand-washing, using protective face covering, disinfecting surfaces you touch a lot, and not sharing personal items with others.

    Receiving a Janssen COVID-19 Vaccine will not cause you to test positive on a coronavirus test. However, once your body develops immunity to COVID-19, you could test positive on an antibody test .

    It is not known how long Janssen COVID-19 Vaccine will protect you from infection with COVID-19. It also is not known how long immunity will last in a person who’s been infected with and recovered from COVID-19. COVID-19 vaccine is still being studied and all of its risks are not yet known.

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