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Updated on June 23, 2022 9:27 pm
All countries
Updated on June 23, 2022 9:27 pm
All countries
Updated on June 23, 2022 9:27 pm

Global Statistics

All countries
Updated on June 23, 2022 9:27 pm
All countries
Updated on June 23, 2022 9:27 pm
All countries
Updated on June 23, 2022 9:27 pm
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Which Covid 19 Vaccine Is Best

Does Johns Hopkins Medicine Recommend I Get A Covid

Which COVID-19 vaccine is the best? | DW News

Yes, we recommend that everyone who is eligible get vaccinated with one of the three currently authorized COVID-19 vaccines. We view all three vaccines as highly efficacious for preventing serious disease, hospitalization and death from COVID-19. Read more about vaccine safety.

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Cdc Expands Eligibility For Covid

Contact:Media Relations 639-3286

Today, CDC Director Rochelle P. Walensky, M.D., M.P.H., endorsed the CDC Advisory Committee on Immunization Practices recommendation for a booster shot of COVID-19 vaccines in certain populations. The Food and Drug Administrations authorizationexternal icon and CDCs recommendation for use are important steps forward as we work to stay ahead of the virus and keep Americans safe.

For individuals who received a Pfizer-BioNTech or Moderna COVID-19 vaccine, the following groups are eligible for a booster shot at 6 months or more after their initial series:

For the nearly 15 million people who got the Johnson & Johnson COVID-19 vaccine, booster shots are also recommended for those who are 18 and older and who were vaccinated two or more months ago.

There are now booster recommendations for all three available COVID-19 vaccines in the United States. Eligible individuals may choose which vaccine they receive as a booster dose. Some people may have a preference for the vaccine type that they originally received, and others may prefer to get a different booster. CDCs recommendations now allow for this type of mix and match dosing for booster shots.

The following is attributable to Dr. Walensky:

Are The Vaccines Safe

Every vaccine that is approved in the United States, even if under emergency use authorization, undergoes stringent safety testing, and the CDC continues to collect data on any side effects or adverse outcomes that could be related to the vaccine over time.

People who receive vaccines may experience a number of side effects, such as a sore arm, fever, fatigue, chills, nausea, and body aches especially after the second dose of one of the two-dose regimens. This is a sign that the immune system is reacting and is not a cause for concern. The CDC recommends taking a painkiller after getting the shot and exercising the arm to avoid soreness.

The side effects are generally more intense after the second shot, as the immune system reacts to the known spike protein. The CDC also reports that 80% of those who reported experiencing side effects were women, which may be related to sex hormones role in the immune response, according to a New York Times article.

There are some rare serious side effects, such as anaphylaxis a life-threatening, but treatable, allergic reaction. In the United States, this reaction has occurred in about two to five people per million vaccinated and has not resulted in any deaths.

The CDC requires that vaccinated people stay at the vaccination site for observation for at least 15 minutes after getting the shot in case they do have a negative reaction.

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The Cdc And Fda Say The Vaccine Is Safe And Effective In Both Pregnant Women And Children As Young As 12 Years Old

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Common searches surrounding the Covid-19 vaccine include people asking if its safe for pregnant women and children as young as 12 years old

As the coronavirus pandemic rages on, health officials have pushed the importance of Covid-19 vaccines in an effort to protect a majority of Americans, and the rest of the world, against the novel virus.

Already 158 million Americans, or 47.7 per cent, have received at least one dose of a Covid-19 vaccine and 124 million Americans, or 37.5 per cent, are fully vaccinated against the virus, according to data released by the Centers for Disease Control and Prevention .

Health officials would now have to reach those who are hesitant about the vaccine, as the country works to reach herd immunity. But questions still remain among some people about the available vaccines safety and efficacy.

The Independent has answered some of the most searched questions about the Covid-19 vaccines.

Additional Vaccines That Are Mandated In The Us


A federal vaccine mandate is not new. In 1977, for example, the federal government began an initiative to vaccinate up to 90% of the nation’s children against seven diseases:

  • Diphtheria

All 50 states require specific vaccines for students, with exemptions varying from state to state. Most school requirements follow the CDC’s vaccine schedule for children.

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Have There Been Any Covid

Issues concerning the Johnson & Johnson COVID-19 vaccine and a rare incidence of myocarditis after the Pfizer and Moderna COVID-19 vaccines, as noted above have been reported.

Trials for the vaccines have had fully independent safety monitoring boards, and safety data are continuously reviewed by the FDA and expert panels. The number of serious problems in test participants was very low, and there was little difference between those who received the actual vaccine and those who received a placebo. Millions of people have received the vaccines since their authorization, and careful safety monitoring of all three COVID-19 vaccines continues.

How Is Cerebral Venous Sinus Thrombosis Treated

The main treatment for CVST is the anticoagulation drug heparin. Heparin and other anticoagulantsor blood thinnersare used to treat CVST because they help to prevent new blood clots from forming in blood vessels throughout the body, including the venous sinuses of the brain, and can keep existing clots from getting larger. Blood thinners, however, cannot dissolve existing clots. Heparin is delivered to the body intravenously or via injection.

If patients do not improve upon administration of heparin or another blood thinner, the doctor may administer thrombolytic enzymes, which can dissolve existing blood clots. Because they may cause hemorrhage, these medications are typically used only in severe cases. Alternatively, a surgeon may perform a procedure known as a thrombectomy to remove the blood clot. The goal of thrombolytic enzymes and thrombectomy is the same: to remove the blood clot and restore blood flow.

Once the acute phase of CVST has been controlled, doctors will transition the patient to an oral blood thinner, such as warfarin. Anticoagulation therapy is continued to prevent recurrence of CVST or other clotting disorders. Patients will typically stay on oral blood thinners for three or more months. Pregnant women, however, should not take warfarin because it may cause birth defects.

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How Long With Coronavirus Vaccines Last

If you are fully vaccinated, you may be excited about gathering with family and friends this summer. But there are still nagging questions about how long protection from the coronavirus vaccines will last. Will it wear off gradually or suddenly? Will you need a booster shot? Unfortunately, we cant answer these questions with certainty yet. Though researchers know the vaccines have been effective against COVID-19 thus far, there is no track record to provide data for the future, which is the only way to know for sure.

We can only say that a vaccine is protective as long as we are measuring it, says Yale Medicine infectious diseases specialist Jaimie Meyer, MD, MS.

In the meantime, there are a few things we do know.

Everyone Affected By The Covid

Why you can’t compare Covid-19 vaccines

Announcing “a new plan to require more Americans to be vaccinated to combat those blocking public health,” Biden on Sept. 9 rolled out his administration’s Path Out of the Pandemic program, which aims to increase the vaccination rate by requiring shots across public and private sectors. Roughly 80 million Americans who are eligible for a COVID-19 vaccine have not been vaccinated. And as of July, 99% of COVID deaths were among the unvaccinated, who also made up 97% of hospitalizations.

Here’s who’s required to be vaccinated under the plan:

  • Employers with 100 or more employees will be required to have their employees either be fully vaccinated or get tested weekly to come to work. Biden said the Department of Labor’s Occupational Safety and Health Administration would implement the requirements that will affect 84 million workers.
  • Federal workers and employees of contractors that do business with the federal government will be required to be vaccinated.
  • The Department of Health and Human Services will require vaccinations in Head Start Programs, as well as schools run by the Department of Defense and the Bureau of Indian Education.
  • Workers in health care facilities that receive Medicare and Medicaid reimbursements, including hospitals and home health agencies, will also have to be fully vaccinated.
  • Individuals applying to become lawful permanent US residents must be fully vaccinated, US Citizenship and Immigration Services announced on Sept. 14.

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Coronavirus Disease : Vaccines

Yes there are now several vaccines that are in use. The first mass vaccination programme started in early December 2020 and the number of vaccination doses administered is updated on a daily basis here. At least 13 different vaccines have been administered.

The Pfizer/BioNtech Comirnaty vaccine was listed for WHO Emergency Use Listing on 31 December 2020. The SII/Covishield and AstraZeneca/AZD1222 vaccines were given EUL on 16 February. The Janssen/Ad26.COV 2.S developed by Johnson & Johnson, was listed for EUL on 12 March 2021. The Moderna COVID-19 vaccine was listed for EUL on 30 April 2021 and the Sinopharm COVID-19 vaccine was listed for EUL on 7 May 2021. The Sinopharm vaccine is produced by Beijing Bio-Institute of Biological Products Co Ltd, subsidiary of China National Biotec Group . The Sinovac-CoronaVac was listed for EUL on 1 June 2021.

For further information, see here.

WHO is on track to EUL other vaccine products through June.

The products and progress in regulatory review by WHO is provided by WHO and updated regularly. The document is provided here.

The first COVID-19 vaccines have already begun to be introduced in countries. Before COVID-19 vaccines can be delivered:

WHO is working with partners around the world to accelerate every step of this process, while also ensuring the highest safety standards are met. More information is available here.

What Do We Know About The Pfizer/biontech Covid

In August 2021, the FDA granted full approval to the Pfizer/BioNTech COVID-19 mRNA vaccine for use in people ages 16 years and older. The transition from emergency use authorization status to full licensure was based on additional data and longer follow-up showing that the vaccine met certain safety, effectiveness, and manufacturing quality standards.

Previous milestones for the Pfizer/BioNTech COVID-19 vaccine include the following:

  • In December 2020, the FDA granted EUA to the Pfizer/BioNTech vaccine in people ages 16 years and older. It was the first COVID-19 vaccine to receive EUA.
  • In May 2021, the FDA expanded its EUA for the Pfizer/BioNTech vaccine to include adolescents 12 to 15 years old.
  • In August 2021, the FDA authorized a third dose of mRNA vaccine for certain people with a weakened immune response.

The FDA granted its original EUA based on their own analysis of efficacy and safety data as well as on the recommendation made by the Vaccines and Related Biological Products Advisory Committee on December 10th. VRBPAC is a group of outside experts in infectious disease, vaccinology, microbiology, immunology, and other related fields.

None of the study participants experienced serious side effects. However, most did have pain at the injection site. Also, about half of those receiving the vaccine reported mild to moderate fatigue or headache or both. Chills and fever were also fairly common. Symptoms almost always resolved within 24 to 48 hours.

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Moderna Maintained Efficacy Up To 5 Months

A recent study by Brigham and Womens Hospital researchers concluded that the Moderna COVID-19 vaccine was 93 percent effective at preventing illness, and more than 98 percent effective for preventing severe illness even 5 months after a second dose.

The vaccine trial included 30,415 participants, with 15,209 receiving Modernas vaccine and 15,206 given a placebo.

According to researchers, the Moderna vaccine showed continued effectiveness at preventing COVID-19 and severe illness even after 5 months, while maintaining an acceptable safety profile and protection against asymptomatic infection.

The message here is not that if you were vaccinated early, youre not protected. Those vaccinated more recently may be experiencing a marginal improvement, co-corresponding author Lindsey Baden, MD, division of infectious diseases at BHW said in a statement. But both groups are benefiting from protection compared to people who remain unvaccinated.

Waning immunity happens to some extent with all vaccines, but that does not mean that the vaccines stop working completely, David Hirschwerk, MD, an infectious disease specialist with Northwell Health in Manhasset, New York, told Healthline.

But their effectiveness often reduces as times moves along, he continued.

He emphasized that COVID-19 vaccines remain very effective at preventing severe illness well beyond 6 months.

But they become steadily less effective at preventing any degree of infection.

Appendix C: Clinical Trial Evidence Summary For Astrazeneca Covid


Results from four clinical trials were available at time of authorization for the AstraZeneca COVID-19 vaccine. Results from an ongoing Phase 3 trial in the United States were not available at time of writing. Evidence on efficacy, immunogenicity, and safety is available for adults â¥18 years of age. The Phase 2/3 trial trial and Phase 3 trial assessed efficacy, safety and immunogenicity of the vaccine. The Phase 2/3 trial was based in the United Kingdom, while the Phase 3 trial was based in Brazil. These two studies underwent a series of protocol amendments and logistical challenges during the conduct of the trials that resulted in significant changes to the trials’ methodology. There were changes from a single to a two-dose vaccine regimen, the use of both a low dose/standard dose and standard dose/standard dose vaccine regimen, and the recruitment of progressively older study participants after the initial focus on adults 18-55 years of age. In the SD/SD vaccine regimen, study participants were randomized to receive either the AstraZeneca COVID-19 vaccine, AZD1222 or control injection. The participants randomized to the control group were administered two doses of quadrivalent meningococcal vaccine or MenACWY for Dose 1 and placebo for Dose 2 .

Evidence from the AstraZeneca COVID-19 vaccine trials has been publishedFootnote 150. Evidence from post-marketing surveillance and studies is found in the main body of this statement.

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Experts Are Excited To Have A Single

The most obvious benefit of the J& J vaccine is it’s just one shot.

“It’s nice to have a single-dose vaccine,” FDA committee member Eric Rubin, editor in chief of the New England Journal of Medicine, said Friday evening after the vote. “The demand is so large that it clearly has a place.”

The rest of the FDA committee agreed.

“What we have to keep in mind is we are still in the midst of this deadly pandemic,” committee member Archana Chatterjee, dean of the Chicago Medical School, said. “There is a shortage of vaccines that are currently authorized, and I think authorization of this vaccine will help meet the needs of the moment.”

Adding millions more shots to the US’s vaccine arsenal will help drive up the collective immunity of the country. And one shot can do that quicker than two. Not only is the J& J vaccine simpler to give out, requiring no second appointments, it’s also significantly cheaper to produce than mRNA shots making it a great tool to fight the pandemic worldwide.

What Are The Symptoms Of Cerebral Venous Sinus Thrombosis

CVST can cause a number of symptoms including:

  • Headache
  • Seizure
  • Nausea, vomiting
  • Weakness or impaired control of one side of the body, both sides of the body, or one leg or one arm
  • Difficulty speaking
  • Blurred or double vision brief periods in which vision becomes gray or black
  • Coma

A patient may experience one or several of these symptoms. While symptoms may appear suddenly, in general they develop over the course of a week or longer. In about a third of cases, headache is the only symptom.

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Why Did The Fda And Cdc Recommend Temporarily Pausing Use Of The Johnson & Johnson Covid

On April 13, 2021, the FDA and CDC jointly recommended pausing use of the Johnson & Johnson COVID-19 vaccine until the agencies could review the cases of a rare but serious type of blood clot that were reported in six women who received the Johnson & Johnson vaccine. On April 23, the FDA and CDC recommended lifting the pause, and allowing use of the vaccine to resume. They made this decision after their medical and scientific teams examined the data and determined that the vaccines known and potential benefits outweigh its known and potential risks.

The Johnson & Johnson vaccine is once again available for use in the US, for anyone ages 18 and older. However, the vaccines label and factsheet will now warn of the rare risk of developing blood clots involving blood vessels in the brain, abdomen, and legs, along with low levels of blood platelets. The label and factsheet also list symptoms of TTS and urge anyone who experiences them after receiving the Johnson & Johnson vaccine to seek immediate medical attention.

Since the FDA granted emergency use authorization for the Johnson & Johnson vaccine in late February, more than 8 million doses of the one-dose vaccine have been given. A total of 15 cases of TTS were reported through April 23rd all occurred in women between the ages of 18 and 59, between six and 15 days after vaccination.

  • severe headache
  • tiny red spots on the skin
  • new or easy bruising or bleeding.

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