Global Statistics

All countries
620,405,933
Confirmed
Updated on September 26, 2022 4:09 pm
All countries
599,160,078
Recovered
Updated on September 26, 2022 4:09 pm
All countries
6,540,798
Deaths
Updated on September 26, 2022 4:09 pm

Global Statistics

All countries
620,405,933
Confirmed
Updated on September 26, 2022 4:09 pm
All countries
599,160,078
Recovered
Updated on September 26, 2022 4:09 pm
All countries
6,540,798
Deaths
Updated on September 26, 2022 4:09 pm
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Which Covid Vaccine Is The Most Effective

Can I Still Get Covid

Which Covid-19 vaccine is most effective?

Cases of infection post-vaccine, called breakthrough cases, are being reported, but experts stress they are still relatively uncommon. Whats more, its rare to get an infection that results in hospitalization or death once you are fully vaccinated. 

According to data collected by the CDC, less than 1 percent of fully vaccinated Americans have been hospitalized or have died from COVID-19. The vast majority of serious illness and death is occurring in unvaccinated individuals. 

Breakthrough infections, however, can contribute to the spread of COVID-19. New data show that fully vaccinated people who become infected with the delta variant can pass the virus on to others, which is why health officials now recommend that vaccinated individuals in areas of high community transmission wear a face mask in indoor public settings. 

The masking recommendation was updated to ensure the vaccinated public would not unknowingly transmit virus to others, including their unvaccinated or immunocompromised loved ones, CDC Director Rochelle Walensky said. 

Safety For Those Who Are Pregnant Or Lactating

None of the vaccines has been tested in these two groups, although Pfizer recently began a Phase 2/3 trial to test the safety and efficacy of its vaccine during pregnancy. Van Hoof said J&J will begin a similar trial in late March or early April.

Moderna has completed animal studies the FDA demanded of manufacturers; these studies look for evidence that the vaccine might harm the pregnancy or the developing fetus. The company said it saw no such signals.

The CDC recommends until those studies are conducted, the choice of whether to get vaccinated should rest with the person who is pregnant or lactating. This is a more permissive stance than has been taken in some countries, which have said people who are pregnant should not be vaccinated with these vaccines.

Are The Vaccines Safe

Safety is a key concern among health officials and experts. Participants in the Pfizer-BioNTech, Moderna and Johnson & Johnson trials experienced side effects after vaccination, including injection-site pain, fever, chills, headaches, muscle aches and joint pain. These symptoms are temporary and are in line with side effects some people experience from other vaccines, including the flu shot and the vaccine to prevent shingles.

More serious reactions are rarer, but they do occur. On April 13, the CDC and FDA recommended that U.S. vaccination sites pause their use of the Johnson & Johnson vaccine while the agencies review data involving six reported cases of a rare but serious type of blood clot, called cerebral venous sinus thrombosis, in individuals after they received the vaccine. One case was fatal and one patient was in critical condition.

All six cases occurred in women between the ages of 18 and 48, six to 13 days after vaccination. People who recently received the Johnson & Johnson vaccine and develop symptoms of severe headache, abdominal pain, leg pain or shortness of breath within three weeks after vaccination should contact their health care provider, officials say.

On April 23, CDCs Advisory Committee on Immunization Practices recommended to the CDC director that the pause be lifted. A notice to women age 50 and under would be added to the fact sheets the government provides to people getting vaccinated.

The latest on how to get the vaccine.

What About The Future

The COVID vaccine you get today is not likely to be your last. As immunity naturally wanes after immunisation, periodic boosters will become necessary to maintain effective protection.

There is now promising data from Spain that mix-and-matching vaccines is safe and can trigger very potent immune responses. So this may be a viable strategy to maintain high vaccine effectiveness over time.

In other words, the best vaccine might in fact be a number of different vaccines.

Variant viruses have started to circulate, and while current vaccines show reduced protection against these variants, they still protect.

Companies, including Moderna, are rapidly updating their vaccines to be administered as variant-specific boosters to combat this.

So, while one vaccine might have a greater efficacy in a phase 3 trial, that vaccine might not necessarily be best at protecting against future variants of concern circulating near you.

Read more:Can I get AstraZeneca now and Pfizer later? Why mixing and matching COVID vaccines could help solve many rollout problems

Do I Need The Vaccine If I Have Already Had Covid

Even if you had COVID-19, the CDC still recommends getting vaccinated. Thats because experts do not yet know how long you are protected from getting sick again after recovering from COVID-19. Even if you have already recovered from COVID-19, it is possible although rare that you could be infected with the virus that causes COVID-19 again, the agency explains.

Have questions? Talk to your doctor.

Essentially, what a vaccine is doing is teaching the immune system how to handle something before you actually encounter the real thing so that, hopefully, when you do encounter the real thing, youre able to deal with it quickly and get rid of it.

Which Vaccine Is Most Effective

The “best” vaccine is the one you are offered, doctors continue to remind the public.EMBED More News Videos

As millions get vaccinated, doctors are noticing patients with allergies or delayed reactions to the Moderna and Pfizer vaccine. What’s causing it? Medical experts explain their findings and say these reactions are temporary.

Myocarditis And The Covid

Since April 2021, there have been more than a thousand reports of cases of myocarditis and pericarditis happening after receiving the Pfizer-BioNTech or Moderna coronavirus vaccines in the United States, according to the U.S. Centers for Disease Control and Prevention .

Considering the hundreds of millions of COVID-19 vaccine doses that have been administered, these reports are very rare. The problem occurs more often in adolescents and young adults, and in males. The myocarditis or pericarditis in most cases is mild and resolves quickly.

Seek medical attention right away if, within a few days of receiving the second injection of an mRNA COVID-19 vaccination , you or your child experiences chest pain, shortness of breath, or feelings of having a fast-beating, fluttering, or pounding heartbeat.

Britain’s 350million Covid Vaccine Doses

THE government has ordered 350million doses of Covid-19 vaccine, with vaccination starting in early December.

This includes 40million doses of the promising Pfizer shot, which was revealed to be 90 per cent effect last week.

These are the other vaccines which the government has pre-ordered:

Oxford/AstraZeneca: 100million dosesA weakened virus that causes colds in chimpanzees, it has been shown to generate a strong immune response against Covid-19.

It has been genetically changed so that it is impossible for it to grow in humans, making it safe for children, the elderly and people with pre-existing conditions.

Currently in phase-3 trials in the UK, USA, South Africa, Japan, Brazil and Kenya, more than 50,000 test patients have been given the vaccine. Early reviews have shown it to be safe.

A company in Australia has already started making millions of vials in the expectation that trials will be successful.

Novavax: 60million doses

Contains purified piece of the virus that causes Covid-19. When it is administered, the body recognises it as foreign and mounts a protective immune response.

It has been shown to generate more antibodies than in patients recovering from severe Covid-19 infections.

Currently in phase-3 clinical trials in the UK and USA.

GSK/Sanofi: 60million doses

What Coronavirus Vaccines Are Available Now

Covid-19 vaccine ‘effective in elderly’

The vaccines from Pfizer-BioNTech, Moderna and Johnson & Johnson are so far the only products available to Americans.

Pfizers vaccine is approved for people 16 and older and is available for people ages 12-15 under emergency use authorization; Moderna and J&J’s vaccines have been authorized for people 18 and older.

The three vaccines have been found to be highly effective at preventing COVID-19 in clinical trial participants and in real-world data. A large study looking at a diverse population of fully vaccinated health care workers found the two-dose mRNA vaccines from Pfizer-BioNTech and Moderna reduced the risk of getting sick with COVID-19 by 94 percent. In a separate study, researchers found the Pfizer-BioNTech and Moderna vaccines were 94 percent effective against COVID-19 hospitalization among fully vaccinated adults 65 years and older.

J&Js product has been found to be 66 percent effective overall and 72 percent effective in U.S.-based clinical trials.

Study Finds Astrazeneca Vaccine Most Effective In Preventing Covid

A new study examining the effectiveness of COVID vaccines has found AstraZeneca is the best at preventing hospitalisation and

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What Do We Know About Chinas Sinovac And Sinopharm Vaccines

Sinovac is one of four Chinese vaccines to have reached the last-stage human trials, a higher number than any other nation in the world.

Along with Sinopharm, it is now being rolled out across the world. Some are concerned about the quality of the vaccines after past scandals over Chinese-made drugs and vaccines. 

Clinical trials in Brazil reported on Jan 13 that Sinovac was 50.4 per cent effective, only slightly above the World Health Organisation’s minimum standard of 50 per cent.

On Jan 11, Indonesia became the first country outside China to grant emergency approval to Sinovacs vaccine, amid surging infections and deaths, followed two days later by Turkey. Interim data showed it is 65.3 per cent effective, Indonesia’s food and drugs authority said.

Sinopharm was approved by the World Health Organisation for use in May, which concluded that the data showed it had an efficacy of 79 per cent. It is now considering Sinovac for use, too. 

Leave your questions about the vaccines below

Protect yourself and your family by learning more about Global Health Security

Vaccines Vs Delta Variant

All three vaccines are proven to be effective in varying degrees against the original variant of the coronavirus, SARS-CoV-2, that causes COVID-19.

However, since the Delta variant emerged, scientists have been trying to establish whether these vaccines are as effective against it.

We broke down what the current data says. But new research could mean this data will change over time.

Pfizer Says Covid Vaccine Is Highly Effective Against Delta Variant

Maayan Lubell

A person walks past a Pfizer logo amid the coronavirus disease pandemic in the Manhattan borough of New York City, New York, U.S., April 1, 2021. REUTERS/Carlo Allegri

JERUSALEM, June 24 – The Pfizer-BioNTech >PFE.N< vaccine is highly effective against the Delta variant of COVID-19, a Pfizer official in Israel said on Thursday.

First identified in India, Delta is becoming the globally dominant variant of the coronavirus, according to the World Health Organization.

“The data we have today, accumulating from research we are conducting at the lab and including data from those places where the Indian variant, Delta, has replaced the British variant as the common variant, point to our vaccine being very effective, around 90%, in preventing the coronavirus disease, COVID-19,” Alon Rappaport, Pfizer’s medical director in Israel, told local broadcaster Army Radio.

A study by researchers from the University of Texas together with Pfizer and BioNtech and published this month by Nature journal found that antibodies elicited by the vaccine were still able to neutralize all tested variants, including Delta, albeit at reduced strength.

Other recent studies have also shown the vaccine is likely to provide high protection against the variant. read more

“We are collecting the data now. We are only now seeing the first cases of the Delta variant in Israel – about 200 of those – so we will know more soon,” she told reporters on Wednesday.

So How Do Vaccines Actually Work

Basically, vaccines train the immune system to recognize dangerous pathogens, like SARS-CoV-2, allowing the body to fight an infection without having to get sick.

The immune system is like an orchestra. It has so many different players and instruments that need to work together to defend the body against invading pathogens, says Akiko Iwasaki, PhD, Waldemar Von Zedtwitz Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale School of Medicine. The vaccine serves as the conductor to orchestrate the defense system. 

How does this happen? When a pathogen infects the body, the immune system dispatches an army of different cells to clear the infection from the body. Two types of immune cells that make up this armyB cells and T cellsare particularly important for the development of vaccines.

How Long Does Protection Against Disease Last

Six months is not much time to collect data on how durable vaccine responses will be, but data could soon emerge from clinical-trial participants who had their first doses last July.

In the meantime, some researchers are looking to natural immunity as a guide. A study in more than 25,000 health-care workers in the United Kingdom found that a SARS-CoV-2 infection reduced the risk of catching the virus again by 84% for at least 7 months. And Abu-Raddad says an unpublished study in Qatar is finding about 90% protection against reinfection as much as a year after a bout of SARS-CoV-2. It seems to suggest that immunity is really strong against this virus, he says. Im optimistic that vaccine immunity is going to last more than a few months and longer than a year, hopefully.

What scientists know about new, fast-spreading coronavirus variants

How soon that booster is needed could depend in part on the rate at which antibody levels decline they could drop precipitously or plateau at a low level. One modelling study estimates that low levels of antibodies will be enough to offer significant protection against severe disease. But Pfizer chief executive Albert Bourla has said that he expects a booster to be needed in about 812 months after the second dose of the PfizerBioNTech vaccine.

How Effective Are The Vaccines Against Variants

Soon after the triumph of Keenans first dose, the world had a fresh reason to worry. A SARS-CoV-2 variant identified in the United Kingdom seemed to be spreading unusually fast; a different variant first identified in South Africa carried worrisome mutations in the coronavirus spike protein that serves as the basis for most COVID-19 vaccines in use.

Since then, further variants of concern have arrived in a steady parade, brandishing mutations that might boost the viruss spread, or undermine the effectiveness of COVID-19 vaccines. Uncontrolled outbreaks generate mutants, says Jerome Kim, director-general of the International Vaccine Institute in Seoul.

Initial laboratory tests suggested that antibodies raised by the PfizerBioNTech vaccine were less effective against the B.1.351 variant identified in South Africa, but it was unclear how that would affect protection against disease. In May, researchers in Qatar published reassuring data showing that people who received two doses of the PfizerBioNTech vaccine were 75% less likely to develop COVID-19 from infection with B.1.351, and were almost completely protected from severe disease. The big question right now is whether introduction of other variants could change the situation, says study author and infectious-disease epidemiologist Laith Jamal Abu-Raddad at Weill Cornell MedicineQatar in Doha. We are watching this on a daily basis, but we have optimism that maybe we have seen the worst.

Is The Moderna Covid Vaccine Safe

Coronavirus vaccine: Here’s why the first COVID-19 might not be the most effective

  • 8:55, 26 Aug 2021
  • Invalid Date,

MODERNA’S Covid vaccine was the third to be added to the UK’s arsenal in fighting the virus.

The is 94 per cent effective against the killer virus and has been given to millions of Brits.

The government said it has secured 350 million doses of Covid vaccines from various pharmaceutical giants.

Trials on more than 30,000 people found that only five given the Moderna jab developed Covid none with severe symptoms.

The UK has secured 100 million doses of Pfizer’s coronavirus vaccine – enough for a third of the population.

Moderna’s jab is easier to distribute than Pfizer’s, which has to be stored at -70C, as it has been shown to last up to 30 days in household fridges.

So far in the UK over 31.6 million Brits have received a first dose of either the Oxford/AstraZeneca or the Pfizer/BioNTech jab with over 5.4 million having had a second.

The Moderna jab will bolster the UK’s vaccine efforts – but how effective is it?

How Effective Are The Vaccines

Going by clinical trial results alone the Pfizer/BioNTech and Moderna jabs have the highest efficacy  scoring 95 per cent and 94.1 per cent respectively. However, as data from mass administration of the vaccines begin to emerge we are getting a clearer picture on the real-world effectiveness of all of the jabs. 

That’s actually even better than the AstraZeneca jab’s trial efficacy results, at 76 per cent after one dose and 82 per cent if the second dose is given 12 weeks later.

Other vaccines do not yet have such strong real-world data to back up trial results.

The J&J vaccine  which was tested in the United States, South Africa and several Latin American countries  had 66 per cent efficacy overall, but this varied depending where it was tested. For example, in the US the vaccine achieved 72 per cent efficacy, but in South Africa  where a new variant was running rampant  it was just 57 per cent.

But, Dr Anthony Fauci, leader of the US response, pointed out that none of the trial participants who took the vaccine  either in the US, South Africa or Latin America  were hospitalised or died. 

The most important thing is to keep people outside hospital and prevent them getting severe disease, he said. 

If You Value Our Coronavirus Coverage Please Consider Making A One

But since the J&J vaccines arrival on the scene there have been a number of challenges. A production snafu in the hands of a contract production company contaminated 15 million doses, which had to be destroyed. And in mid-April, the FDA and CDC recommended states pause use of the vaccine as they investigate whether the vaccine triggers a rare but serious side effect the development of diffuse blood clots, even though the few individuals who developed the condition had low platelet levels.

What follows is a head-to-head comparison of the vaccines developed by Pfizer and BioNTech, by Moderna, and by J&J. This article will be updated as developments occur.

Six Months Of Covid Vaccines: What 17 Billion Doses Have Taught Scientists

Nature

Over the past six months, hundreds of millions of people around the world have rushed to follow in the footsteps of a 90-year-old British woman named Margaret Keenan.

At 6:30 a.m. on 8 December 2020, Keenan became the first person to receive a COVID-19 vaccine as part of a mass vaccination effort. Her shot was the culmination of a frenzied effort to develop vaccines safely and in record time. Now, more than 1.7 billion doses later , researchers are sifting through the data to address lingering questions about how well the vaccines work and how they might shape the course of the coronavirus pandemic that has already taken more than 3.5 million lives.

Its absolutely astonishing that this has happened in such a short time to me, its equivalent to putting a person on the Moon, says paediatric infectious-disease specialist Cody Meissner at Tufts University School of Medicine and Tufts Childrens Hospital in Boston, Massachusetts. This is going to change vaccinology forever.

Nature looks at what lessons have emerged during the first six months of COVID-19 vaccinations, as well as what questions still linger. Overall, the vaccine results have been extremely promising even better than many had hoped but researchers have concerns about emerging variants and the potential for immune responses to wane.

What Exactly Is A Vaccine

A vaccine is something that helps a person build up immunity to an infectious disease. It works by intentionally introducing the body to an inactive form of a disease-causing germ, or something similar to it. This then stimulates the immune systems production of antibodies, the proteins that help to protect the person from a future infection if he ever comes across the real germ.

Think of it like a workout for your immune system: Youre sending it to the gym and preparing it to be able to do something when it encounters the real thing in the future, says Tony Moody, associate professor of pediatrics and immunology at Duke University School of Medicine and a principal investigator at the Duke Human Vaccine Institute. Essentially, what a vaccine is doing is teaching the immune system how to handle something before you actually encounter the real thing so that, hopefully, when you do encounter the real thing, youre able to deal with it quickly and get rid of it.

In the case of the new coronavirus, a vaccine makes a person resistant to an infection from the virus and the illness it causes COVID-19 or, at least, enables a person who becomes infected to have a shorter course or not as many complications, Moody adds.

For the latest coronavirus news and advice go to AARP.org/coronavirus.

Zydus Cadila: What We Know About India’s New Covid Vaccines

India has given a boost to its vaccination programme by approving its first vaccine for those under 18.

The three-dose ZyCoV-D vaccine prevented symptomatic disease in 66% of those vaccinated, according to an interim study quoted by the vaccine maker Cadila Healthcare.

This is also the first time, the firm claimed, a Covid-19 vaccine had been tested in young people in India. The jab was found to be “safe and very well-tolerated” in this age group.

India has so far given more than 570 million doses of three previously approved vaccines – Covishield, Covaxin and Sputnik V. The government aims to vaccinate all Indians by the end of this year.

About 13% of eligible adults have been fully vaccinated and 47% have received at least one shot since the beginning of the drive in January.

India has reported more than 32 million Covid cases, second only to the US. The country is also only the third in the world to record more than 400,000 deaths – behind the US and Brazil.

The Best Vaccine Is The One You Can Get Now

It is entirely rational to want the best vaccine available. But the best vaccine is the one available to you right now because it stops you from catching COVID-19, reduces transmission to vulnerable members of our community and substantially reduces your risk of severe disease.

All available vaccines do this job and do it well. From a collective perspective, these benefits are compounded. The more people get vaccinated, the more the community becomes immune , further curtailing the spread of COVID-19.

The global pandemic is a highly dynamic situation, with emerging viral variants of concern, uncertain global vaccine supply, patchy governmental action and potential for explosive outbreaks in many regions.

So waiting for the perfect vaccine is an unattainable ambition. Every vaccine delivered is a small but significant step towards global normality.

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